中华手外科杂志
中華手外科雜誌
중화수외과잡지
CHINESE JOURNAL OF HAND SURGERY
2011年
2期
73-76
,共4页
冯俊涛%王涛%陈亮%罗鹏波%顾玉东
馮俊濤%王濤%陳亮%囉鵬波%顧玉東
풍준도%왕도%진량%라붕파%고옥동
神经纤维%神经移位%周围神经%颈7
神經纖維%神經移位%週圍神經%頸7
신경섬유%신경이위%주위신경%경7
Nerve fibers%Nerve transfer%Peripheral nerves%C7
目的 以大鼠健侧颈7直接修复臂丛神经下干为模型,探讨阻断下干分支前后,尺神经和正中神经神经纤维数量和质量的变化.方法 雌性SD大鼠40只,随机分成4组.A组:健侧颈7直接修复下干,并从下干发出处阻断下干后股、胸前内侧神经、前臂内侧皮神经;B组:健侧颈7直接修复下干,并从下干发出处以远1 cm处阻断下干后股、胸前内侧神经、前臂内侧皮神经;C组:健侧颈7直接修复下干,并从下干发出处切断后股;D组:对照组.术后比较尺神经、正中神经、胸前内侧神经和前臂内侧皮神经的神经纤维数量、神经纤维密度(p)、神经纤维数占下干神经纤维总数百分比、神经纤维直径、有髓神经纤维面积与相应分支神经总面积比(N Ratio).结果 尺神经和正中神经中,神经纤维数量、神经纤维密度、正中神经与尺神经分别占下干神经纤维百分比、神经纤维直径、不同直径神经纤维百分比、N Ratio,A、B、C三组间差异均无统计学意义.前臂内侧皮神经和胸前内侧神经中,上述各检测指标B、C组间均无明显差异.结论 健侧颈7直接移位下干后,在根部及根部以远1 cm处阻断胸前内侧神经及前臂内侧皮神经后,对尺神经、正中神经、前臂内侧皮神经残端和胸前内侧神经残端中神经纤维的数量和质量无明显影响.
目的 以大鼠健側頸7直接脩複臂叢神經下榦為模型,探討阻斷下榦分支前後,呎神經和正中神經神經纖維數量和質量的變化.方法 雌性SD大鼠40隻,隨機分成4組.A組:健側頸7直接脩複下榦,併從下榦髮齣處阻斷下榦後股、胸前內側神經、前臂內側皮神經;B組:健側頸7直接脩複下榦,併從下榦髮齣處以遠1 cm處阻斷下榦後股、胸前內側神經、前臂內側皮神經;C組:健側頸7直接脩複下榦,併從下榦髮齣處切斷後股;D組:對照組.術後比較呎神經、正中神經、胸前內側神經和前臂內側皮神經的神經纖維數量、神經纖維密度(p)、神經纖維數佔下榦神經纖維總數百分比、神經纖維直徑、有髓神經纖維麵積與相應分支神經總麵積比(N Ratio).結果 呎神經和正中神經中,神經纖維數量、神經纖維密度、正中神經與呎神經分彆佔下榦神經纖維百分比、神經纖維直徑、不同直徑神經纖維百分比、N Ratio,A、B、C三組間差異均無統計學意義.前臂內側皮神經和胸前內側神經中,上述各檢測指標B、C組間均無明顯差異.結論 健側頸7直接移位下榦後,在根部及根部以遠1 cm處阻斷胸前內側神經及前臂內側皮神經後,對呎神經、正中神經、前臂內側皮神經殘耑和胸前內側神經殘耑中神經纖維的數量和質量無明顯影響.
목적 이대서건측경7직접수복비총신경하간위모형,탐토조단하간분지전후,척신경화정중신경신경섬유수량화질량적변화.방법 자성SD대서40지,수궤분성4조.A조:건측경7직접수복하간,병종하간발출처조단하간후고、흉전내측신경、전비내측피신경;B조:건측경7직접수복하간,병종하간발출처이원1 cm처조단하간후고、흉전내측신경、전비내측피신경;C조:건측경7직접수복하간,병종하간발출처절단후고;D조:대조조.술후비교척신경、정중신경、흉전내측신경화전비내측피신경적신경섬유수량、신경섬유밀도(p)、신경섬유수점하간신경섬유총수백분비、신경섬유직경、유수신경섬유면적여상응분지신경총면적비(N Ratio).결과 척신경화정중신경중,신경섬유수량、신경섬유밀도、정중신경여척신경분별점하간신경섬유백분비、신경섬유직경、불동직경신경섬유백분비、N Ratio,A、B、C삼조간차이균무통계학의의.전비내측피신경화흉전내측신경중,상술각검측지표B、C조간균무명현차이.결론 건측경7직접이위하간후,재근부급근부이원1 cm처조단흉전내측신경급전비내측피신경후,대척신경、정중신경、전비내측피신경잔단화흉전내측신경잔단중신경섬유적수량화질량무명현영향.
Objective To explore the changes of the nerve fibers from median and ulnar nerves after cutting the branches of lower trunk which was repaired by the contralateral C7.Methods Forty female SD rats were divided into A, B, C and D groups randomly.In group A,the contralateral C7 root was transferred to lower trunk directly, and the posterior division of lower trunk, medial anterior thoracic nerve and the medial antebrachial cutaneous nerve were severed at the beginning of them;In group B, the contralateral C7 root was trarsferred to lower trunk directly, and the posterior division of lower trunk, medial anterior thoracic nerve and the medial antebrachial cutaneous nerve were severed at the point which was 1 cm away from the beginning of above branches;In group C, the contralateral C7 root was transferred to lower trunk directly, and the posterior division of lower trunk was severed at the beginning of it;In group D, control group.After the operation, myelinated fiber count, nerve fiber density, the percentage of the number of nerve fiber from branch accounting for that from lower trunk, nerve fiber diameter,the percentage of nerve fibers with different diameters and N Ratio were carried out to evaluate the outcome of each group.Results Myelinated fiber count, nerve fiber density, the percentage of the number of nerve fiber from branch accounting for that from lower trunk, nerve fiber diameter,the percentage of nerve fibers with different diameters and N Ratio in ulnar and median nerve, there were no difference between group A, group B and group C ( P ＞ 0.05).Conclusion After the medial anterior thoracic nerve and medial antebrachial cutaneous nerve, repaired by the contralateral C7, were severed at the beginning and at the point which was 1 cm away from the beginning of above branches, the changes of the quantity and quality of the nerve fibers from median and ulnar nerves were not significant.
