中国临床康复
中國臨床康複
중국림상강복
CHINESE JOURNAL OF CLINICAL REHABILITATION
2005年
15期
231-233
,共3页
藕节%茶%三七%减肥药
藕節%茶%三七%減肥藥
우절%다%삼칠%감비약
背景:肥胖是一个已确立的心血管疾病、糖尿病、高血压、动脉硬化和脑卒中的危险因素.一些激动剂,如麻黄素、咖啡因以及它们的草药类似物质已被证明有减轻体质量的作用,但是对它们的使用因其副反应而有争议.因此,一种能增加能量消耗或减少热量摄入,减肥有效而又能耐受的营养性制剂,是合乎需要的.目的:评估一种含藕节,绿茶及三七成分的新颖微丸制剂,对成年肥胖者体质量和脂肪的减少效果.设计:以自愿者为观察对象,随机,双盲,安慰剂对照实验.单位:云南白药集团天然药物研究院.对象:实验于2003-07-05/08-23在云南白药集团天然药物研究院完成.自愿者82例,男35例,女47例;年龄26～50岁;体质量指数≥25 kg/m2.随机分为处理组和安慰剂组,每组各41例.方法:处理组口服含藕节、绿茶及三七微丸制剂(千草美姿减肥旨安微丸)9 g/d;安慰剂组每天口服淀粉制作微丸9 g/d,实验周期为7周.测量实验起始和实验结束时的体质量,体脂百分含量,脂肪绝对质量,体质量指数,腹围和臀围,以及其他人体测量指标.实验最初3 d和实验末尾3 d记录摄食情况.受试者记录每周的活动情况.主要观察指标:①终点结局指标:两组体质量、身体脂肪含量、体质量指数、腹围及臀围.②替代指标:两组饮食、心率、耗氧量和血压情况.③危险性指标:不良事件和副反应.结果:处理组1例,安慰剂组3例因与实验无关的个人原因退出实验,未进入结果分析.两组摄入的食物总热量及蛋白质、碳水化合物和脂肪的百分比,以及活动水平差异无显著性意义.处理组体质量、身体脂肪含量、体质量指数实验前分别为(74.7±11.4)kg,(33.0±4.1)%,(28.5±2.7)kg/m2;实验7周分别为(73.6±12.4)kg,(31.3 ±4.5)%,(27.9±3.0)kg/m2.前后比较,差异有显著性意义.处理组腹围和臀围也明显缩小.安慰剂组实验前后比较,差异无显著性意义.两组心率,耗氧量及血压差异无显著性意义.两组均无明显副反应.结论:这种含藕节,绿茶及三七成分的新颖微丸制剂,能明显减少成年肥胖者的体质量和脂肪.
揹景:肥胖是一箇已確立的心血管疾病、糖尿病、高血壓、動脈硬化和腦卒中的危險因素.一些激動劑,如痳黃素、咖啡因以及它們的草藥類似物質已被證明有減輕體質量的作用,但是對它們的使用因其副反應而有爭議.因此,一種能增加能量消耗或減少熱量攝入,減肥有效而又能耐受的營養性製劑,是閤乎需要的.目的:評估一種含藕節,綠茶及三七成分的新穎微汍製劑,對成年肥胖者體質量和脂肪的減少效果.設計:以自願者為觀察對象,隨機,雙盲,安慰劑對照實驗.單位:雲南白藥集糰天然藥物研究院.對象:實驗于2003-07-05/08-23在雲南白藥集糰天然藥物研究院完成.自願者82例,男35例,女47例;年齡26～50歲;體質量指數≥25 kg/m2.隨機分為處理組和安慰劑組,每組各41例.方法:處理組口服含藕節、綠茶及三七微汍製劑(韆草美姿減肥旨安微汍)9 g/d;安慰劑組每天口服澱粉製作微汍9 g/d,實驗週期為7週.測量實驗起始和實驗結束時的體質量,體脂百分含量,脂肪絕對質量,體質量指數,腹圍和臀圍,以及其他人體測量指標.實驗最初3 d和實驗末尾3 d記錄攝食情況.受試者記錄每週的活動情況.主要觀察指標:①終點結跼指標:兩組體質量、身體脂肪含量、體質量指數、腹圍及臀圍.②替代指標:兩組飲食、心率、耗氧量和血壓情況.③危險性指標:不良事件和副反應.結果:處理組1例,安慰劑組3例因與實驗無關的箇人原因退齣實驗,未進入結果分析.兩組攝入的食物總熱量及蛋白質、碳水化閤物和脂肪的百分比,以及活動水平差異無顯著性意義.處理組體質量、身體脂肪含量、體質量指數實驗前分彆為(74.7±11.4)kg,(33.0±4.1)%,(28.5±2.7)kg/m2;實驗7週分彆為(73.6±12.4)kg,(31.3 ±4.5)%,(27.9±3.0)kg/m2.前後比較,差異有顯著性意義.處理組腹圍和臀圍也明顯縮小.安慰劑組實驗前後比較,差異無顯著性意義.兩組心率,耗氧量及血壓差異無顯著性意義.兩組均無明顯副反應.結論:這種含藕節,綠茶及三七成分的新穎微汍製劑,能明顯減少成年肥胖者的體質量和脂肪.
배경:비반시일개이학립적심혈관질병、당뇨병、고혈압、동맥경화화뇌졸중적위험인소.일사격동제,여마황소、가배인이급타문적초약유사물질이피증명유감경체질량적작용,단시대타문적사용인기부반응이유쟁의.인차,일충능증가능량소모혹감소열량섭입,감비유효이우능내수적영양성제제,시합호수요적.목적:평고일충함우절,록다급삼칠성분적신영미환제제,대성년비반자체질량화지방적감소효과.설계:이자원자위관찰대상,수궤,쌍맹,안위제대조실험.단위:운남백약집단천연약물연구원.대상:실험우2003-07-05/08-23재운남백약집단천연약물연구원완성.자원자82례,남35례,녀47례;년령26～50세;체질량지수≥25 kg/m2.수궤분위처리조화안위제조,매조각41례.방법:처리조구복함우절、록다급삼칠미환제제(천초미자감비지안미환)9 g/d;안위제조매천구복정분제작미환9 g/d,실험주기위7주.측량실험기시화실험결속시적체질량,체지백분함량,지방절대질량,체질량지수,복위화둔위,이급기타인체측량지표.실험최초3 d화실험말미3 d기록섭식정황.수시자기록매주적활동정황.주요관찰지표:①종점결국지표:량조체질량、신체지방함량、체질량지수、복위급둔위.②체대지표:량조음식、심솔、모양량화혈압정황.③위험성지표:불량사건화부반응.결과:처리조1례,안위제조3례인여실험무관적개인원인퇴출실험,미진입결과분석.량조섭입적식물총열량급단백질、탄수화합물화지방적백분비,이급활동수평차이무현저성의의.처리조체질량、신체지방함량、체질량지수실험전분별위(74.7±11.4)kg,(33.0±4.1)%,(28.5±2.7)kg/m2;실험7주분별위(73.6±12.4)kg,(31.3 ±4.5)%,(27.9±3.0)kg/m2.전후비교,차이유현저성의의.처리조복위화둔위야명현축소.안위제조실험전후비교,차이무현저성의의.량조심솔,모양량급혈압차이무현저성의의.량조균무명현부반응.결론:저충함우절,록다급삼칠성분적신영미환제제,능명현감소성년비반자적체질량화지방.
BACKGROUND: Obesity is a well-established risk factor for cardiovascular diseases, diabetes, hypertension, arteriosclerosis and stroke. Stimulants such as ephedrine and caffeine and their herbal counterparts have been proved effective in reducing body mass; however, their use is controversial due to the undesired effects. Therefore, it is necessary to find a tolerable and effective nutraceutical that can increase energy expenditure and/or decrease calorie intake to reduce weight.OBJECTIVE: To assess the effects of a preparation containing node of Lotus Rhizome, green tea, and Panax notoginsengin reducing body mass and fat in obese adults.DESIGN: Randomized, double blind, placebo-controlled study using the volunteers as the subjects.SETTING: Institute of Natural Drug of Yunnan Baiyao Group.PARTICIPANTS: The trial was conducted in the Institute of Natural Drug of Yunnan Baiyao Group from July 5 to August 23 in 2003. Altogether 82 obese volunteers[35 men and 47 women aged 26- 50 years, body mass index (BMI) ≥ 25 kg/m2 ] were randomly assigned to treatment and placebo groups with 41 in each group.METHODS: The treatment group received 9 g pill of a dietary supplement containing a proprietary blend of node of Lotus Rhizome, green tea and Panax notoginseng every day for 7 weeks, while the placebo group received 9 g pill of rice flour every day for 7 weeks. Their body mass, percentage of body fat,absolute fat mass, BMI, waist and hip circumference, and anthropometric measurements were recorded at the beginning and the end of the study. The subjects completed daily dietary intake records on days 1 to 3 and 47 to 49. They also completed weekly activity logs throughout the study.MAIN OUTCOME MEASURES: ① Final outcome indexes: body mass,percentage of body fat, BMI, waist and hip circumference; ② Replacement indexes: diet, heart rate, oxygen consumption and blood pressure; ③ Risk indexes: adverse events and side effects.RESULTS: Four subjects (1 from the treatment group and 3 from the placebo group) dropped out for personal reasons unrelated to the study. No significant changes were found in the consumption of total calories, percentage of calories ingested as carbohydrates, fat or protein, or activity levels in either
group throughout the study. Body mass, percentage of body fat and BMI of the treatment group were(74.7 ± 11.4) kg, (33.0±4. 1)% and(28.5±2.7) kg/m2 before the experiment, and(73.6 ± 12.4) kg, (31.3 ±4.5)%and(27.9 ± 3.0) kg/m2 at week 7, with significant differences. Waist and hip circumference of the treatment group was obviously decreased, but did not differ significantly before and after the experiment in the placebogroup. There were no significant differences in heart rate, oxygen consumption and blood pressure between the two groups. No obvious side effects were observed in the two groups.CONCLUSION: The novel combination of node of Lotus Rhizome, green tea and Panax notoginseng can significantly reduce body mass and fat in obese adults.
