中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
8期
1125-1126
,共2页
林蔷%陈敬国%郑铠军%夏荣华%黄惠娟%杨秀芳%陈简%叶春华
林薔%陳敬國%鄭鎧軍%夏榮華%黃惠娟%楊秀芳%陳簡%葉春華
림장%진경국%정개군%하영화%황혜연%양수방%진간%협춘화
窒息,新生儿%低温,人工
窒息,新生兒%低溫,人工
질식,신생인%저온,인공
Asphyxia neonatorum%Hypothermia,induced
目的 研究选择性头部亚低温对足月新生儿重度窒息的早期干预效果.方法 将42例足月重度窒息新生儿分为干预组22例,对照组20例,全部患儿治疗复苏后在三项支持、三项对症治疗方案进行治疗的基础上,干预组加用选择性头部亚低温治疗,两组均于治疗后72h测心率、呼吸效率、血压、经皮测血氧饱和度(SpO2)、血糖,两组均于出生28d采用中国20项新生儿神经行为评分,并于出生后2个月做Bayley婴儿量表检查.结果 治疗后72 h干预组心率减慢,与对照组差异有统计学意义(P<0.05),停止治疗后恢复正常;出生28 d新生儿神经行为评分治疗组(37±3)分,对照组(31±3)分,差异有统计学意义(P<0.01);出生后2个月婴儿发育量表干预组(91±3)分,对照组(86±4)分,差异有统计学意义(P<0.05).结论 亚低温治疗重度窒息安全、简便,疗效可靠,对于减轻脑损伤,提高生存质量有积极作用.
目的 研究選擇性頭部亞低溫對足月新生兒重度窒息的早期榦預效果.方法 將42例足月重度窒息新生兒分為榦預組22例,對照組20例,全部患兒治療複囌後在三項支持、三項對癥治療方案進行治療的基礎上,榦預組加用選擇性頭部亞低溫治療,兩組均于治療後72h測心率、呼吸效率、血壓、經皮測血氧飽和度(SpO2)、血糖,兩組均于齣生28d採用中國20項新生兒神經行為評分,併于齣生後2箇月做Bayley嬰兒量錶檢查.結果 治療後72 h榦預組心率減慢,與對照組差異有統計學意義(P<0.05),停止治療後恢複正常;齣生28 d新生兒神經行為評分治療組(37±3)分,對照組(31±3)分,差異有統計學意義(P<0.01);齣生後2箇月嬰兒髮育量錶榦預組(91±3)分,對照組(86±4)分,差異有統計學意義(P<0.05).結論 亞低溫治療重度窒息安全、簡便,療效可靠,對于減輕腦損傷,提高生存質量有積極作用.
목적 연구선택성두부아저온대족월신생인중도질식적조기간예효과.방법 장42례족월중도질식신생인분위간예조22례,대조조20례,전부환인치료복소후재삼항지지、삼항대증치료방안진행치료적기출상,간예조가용선택성두부아저온치료,량조균우치료후72h측심솔、호흡효솔、혈압、경피측혈양포화도(SpO2)、혈당,량조균우출생28d채용중국20항신생인신경행위평분,병우출생후2개월주Bayley영인량표검사.결과 치료후72 h간예조심솔감만,여대조조차이유통계학의의(P<0.05),정지치료후회복정상;출생28 d신생인신경행위평분치료조(37±3)분,대조조(31±3)분,차이유통계학의의(P<0.01);출생후2개월영인발육량표간예조(91±3)분,대조조(86±4)분,차이유통계학의의(P<0.05).결론 아저온치료중도질식안전、간편,료효가고,대우감경뇌손상,제고생존질량유적겁작용.
Objective To study the curative effect of early intervention on selective head sub-hypothermia in full term infant with severe asphyxia.Methods Forty two full term infant with severe asphyxia were randomly divided into treatment(n =22) and control ( n =20) group,all patients were treated according to "three supportive therapy and three heteropathy" after resuscitation,and meanwhile the treament group combined with selective head sub-hypothermia.In the 2 groups,heart and breath oxygen saturation,blood sugar were measurded within 72 hours after treatment,and the Chinese 20-item neonate nerve behaviors were evaluated 28 days after birth.Test were conducted with the Bayley infant development scale in 2 months after birth.Results After 72 hours of treatment,the heart rate of treatment group reduced and showed significant difference from that of contol group and restored to normal.There were no significant differences in breath,blood pressure(BP),degree of blood ozygen saturation,blood sugar between the 2 groups.After 28 days of birth,scores of neonate nerve behaviors were ( 37 ± 3) in treatment group and (31 ± 3) in control group,respectively ;which showed significant difference ( P < 0.01 ).In the 2nd months of birth,scores of Bayley infant development scale were (91 ± 3 ) in treatment group and ( 86 ± 4 ) in control group,respectively,which showed significant difference(P < 0.05 ).Conclusion Selective head sub-hypothermia was convenient and safe,and had reliable curative effect by relieving or prenventing sequel and raising quality of life.