中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2010年
15期
17-19
,共3页
听觉丧失,感音神经性%中耳%地塞米松
聽覺喪失,感音神經性%中耳%地塞米鬆
은각상실,감음신경성%중이%지새미송
Hearing loss,sensorineural%Ear,middle%Dexamethasone
目的 分析鼓室内注射地塞米松对经常规治疗无效突发性耳聋的治疗效果.方法 选择44例经常规治疗无效的突发性耳聋患者,按机械抽样法随机分为鼓室内注射组24例和对照组20例,对照组给予常规治疗,鼓室内注射组在耳显微镜下往鼓膜内缓慢注入地塞米松2.5 mg.结果 鼓室内注射组总有效率(37.5%,9/24)明显高于对照组(10.0%,2/20),差异有统计学意义(P<0.05).鼓室内注射组纯音听阈治疗后[(52.75±20.14)dB]较治疗前[(70.26±20.76)dB]明显改善(P<0.05),同时也优于对照组治疗后[(63.55±19.36)dB](P<0.05).结论 鼓室内注射地塞米松可作为常规治疗无效的突发性耳聋患者的挽救治疗手段,亦可作为避免全身大剂量使用激素不良反应的常规治疗手段之一.
目的 分析鼓室內註射地塞米鬆對經常規治療無效突髮性耳聾的治療效果.方法 選擇44例經常規治療無效的突髮性耳聾患者,按機械抽樣法隨機分為鼓室內註射組24例和對照組20例,對照組給予常規治療,鼓室內註射組在耳顯微鏡下往鼓膜內緩慢註入地塞米鬆2.5 mg.結果 鼓室內註射組總有效率(37.5%,9/24)明顯高于對照組(10.0%,2/20),差異有統計學意義(P<0.05).鼓室內註射組純音聽閾治療後[(52.75±20.14)dB]較治療前[(70.26±20.76)dB]明顯改善(P<0.05),同時也優于對照組治療後[(63.55±19.36)dB](P<0.05).結論 鼓室內註射地塞米鬆可作為常規治療無效的突髮性耳聾患者的輓救治療手段,亦可作為避免全身大劑量使用激素不良反應的常規治療手段之一.
목적 분석고실내주사지새미송대경상규치료무효돌발성이롱적치료효과.방법 선택44례경상규치료무효적돌발성이롱환자,안궤계추양법수궤분위고실내주사조24례화대조조20례,대조조급여상규치료,고실내주사조재이현미경하왕고막내완만주입지새미송2.5 mg.결과 고실내주사조총유효솔(37.5%,9/24)명현고우대조조(10.0%,2/20),차이유통계학의의(P<0.05).고실내주사조순음은역치료후[(52.75±20.14)dB]교치료전[(70.26±20.76)dB]명현개선(P<0.05),동시야우우대조조치료후[(63.55±19.36)dB](P<0.05).결론 고실내주사지새미송가작위상규치료무효적돌발성이롱환자적만구치료수단,역가작위피면전신대제량사용격소불량반응적상규치료수단지일.
Objective To observe the clinical efficacy of intratympanic dexamethasone injection for patients with sudden sensorineural hearing loss (SSNHL). Methods Forty-four SSNHL cases (44 ears) which failed to respond to regular treatments were divided into two groups. The intratympanic injection group (24 eases) were injected dexamethasone 2.5 mg to the tympanic cavity every two days,4 times in all. The control group (20 eases) were treated with B1,B12 and triphosaden. Pure tone average (PTA) was tested before and 3 days after treatment. Results The total effective rate of intratympanic injection group was higher than that of control group [37.5%(9/24) vs 10.0%(2/20)] (P < 0.05). In intratympanic injection group, PTA of post-injection was significantly lower than the pre-injection[ (52.75±20.14) dB vs (70.26±20.76) dB ] (P < 0.05). PTA of post-injection in intratympanic injection group was significantly better than that in control group[(52.75±20.14) dB vs (63.55±19.36) dB](P< 0.05). Conclusion Intratympanic dexamethasone injection can be applied to SSNHL patients who failed to respond to systemic corticosteroid treatment and it can avoid the side effects brought on by high dose systemic corticosteroid treatment.
