中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2012年
1期
15-18
,共4页
肺炎%微量元素%维生素%婴幼儿
肺炎%微量元素%維生素%嬰幼兒
폐염%미량원소%유생소%영유인
Pneumonia%Trace elements%Vitamin%Infant and child
目的 探讨肺炎患儿血清某些维生素及微量元素水平变化.方法 以2010年10月01日至2011年03月01日淮安市第一人民医院门诊及住院肺炎患儿120例作为研究对象.以保健门诊就诊的60名健康同龄儿作为对照.分别应用高效液相色谱法检测血清维生素A水平,原子吸收光谱法测定血清钙、铁、镁、锌含量,酶联免疫法检测血清25-羟基维生素D水平.采用t检验比较两组血清维生素及微量元素含量的差异,采用x2检验比较两组血清维生素及微量元素缺乏率的差异.结果 肺炎组铁、锌、维生素A的缺乏率分别为35.36％、37.09％、46.59％,均显著高于对照组(18.76％,x2=4.32；20.08％,x2 =4.15; 25.08％,x2 =5.81;P均＜0.05).肺炎组与对照组间钙、镁及维生素D缺乏率的差异均无统计学意义(P均＞0.05).肺炎组的血清锌[(16.07±3.56)比(23.24±4.05) μmol/L,t=15.82,P＜0.05]、铁[(19.89±4.79)比(25.13±5.07) μmol/L,t=6.65,P＜0.05]、维生素A含量[ (365.76±35.37)比(451.09±32.16) μg/L,t=2.14,P＜0.05]均显著低于对照组；两组血清钙、镁和25-羟基维生素D含量的差异均无统计学意义(P均＞0.05).结论 肺炎患儿普遍存在锌、铁、维生素A缺乏.
目的 探討肺炎患兒血清某些維生素及微量元素水平變化.方法 以2010年10月01日至2011年03月01日淮安市第一人民醫院門診及住院肺炎患兒120例作為研究對象.以保健門診就診的60名健康同齡兒作為對照.分彆應用高效液相色譜法檢測血清維生素A水平,原子吸收光譜法測定血清鈣、鐵、鎂、鋅含量,酶聯免疫法檢測血清25-羥基維生素D水平.採用t檢驗比較兩組血清維生素及微量元素含量的差異,採用x2檢驗比較兩組血清維生素及微量元素缺乏率的差異.結果 肺炎組鐵、鋅、維生素A的缺乏率分彆為35.36％、37.09％、46.59％,均顯著高于對照組(18.76％,x2=4.32；20.08％,x2 =4.15; 25.08％,x2 =5.81;P均＜0.05).肺炎組與對照組間鈣、鎂及維生素D缺乏率的差異均無統計學意義(P均＞0.05).肺炎組的血清鋅[(16.07±3.56)比(23.24±4.05) μmol/L,t=15.82,P＜0.05]、鐵[(19.89±4.79)比(25.13±5.07) μmol/L,t=6.65,P＜0.05]、維生素A含量[ (365.76±35.37)比(451.09±32.16) μg/L,t=2.14,P＜0.05]均顯著低于對照組；兩組血清鈣、鎂和25-羥基維生素D含量的差異均無統計學意義(P均＞0.05).結論 肺炎患兒普遍存在鋅、鐵、維生素A缺乏.
목적 탐토폐염환인혈청모사유생소급미량원소수평변화.방법 이2010년10월01일지2011년03월01일회안시제일인민의원문진급주원폐염환인120례작위연구대상.이보건문진취진적60명건강동령인작위대조.분별응용고효액상색보법검측혈청유생소A수평,원자흡수광보법측정혈청개、철、미、자함량,매련면역법검측혈청25-간기유생소D수평.채용t검험비교량조혈청유생소급미량원소함량적차이,채용x2검험비교량조혈청유생소급미량원소결핍솔적차이.결과 폐염조철、자、유생소A적결핍솔분별위35.36％、37.09％、46.59％,균현저고우대조조(18.76％,x2=4.32；20.08％,x2 =4.15; 25.08％,x2 =5.81;P균＜0.05).폐염조여대조조간개、미급유생소D결핍솔적차이균무통계학의의(P균＞0.05).폐염조적혈청자[(16.07±3.56)비(23.24±4.05) μmol/L,t=15.82,P＜0.05]、철[(19.89±4.79)비(25.13±5.07) μmol/L,t=6.65,P＜0.05]、유생소A함량[ (365.76±35.37)비(451.09±32.16) μg/L,t=2.14,P＜0.05]균현저저우대조조；량조혈청개、미화25-간기유생소D함량적차이균무통계학의의(P균＞0.05).결론 폐염환인보편존재자、철、유생소A결핍.
Objective To investigate the serum levels of certain vitamins and trace elements in infant and children with pneumonia.Methods Totally 120 pediatric patients with pneumonia who were treated in our hospital were enrolled in the study.Meanwhile,60 age-matched healthy children were randomly selected as the control group.The serum vitamin A level was analyzed using high-performance liquid chromatography.The serum 25-hydroxy vitamin D level was analyzed using enzyme linked immunosorbent assay.The serum zinc,calcium,magnesium,and iron contents were detected using atomic absorption spectrometry.The differences of serum levels of vitamins and trace elements as well as the ratios of vitamins and trace elements deficiency were compared between these two groups.Results The rates of iron,zinc,and vitamin A deficiencies were 35.36％,37.09％,and 46.59％,respectively,in pediatric patients with pneumonia,which were significantly higher than those in the control group ( 18.76％,x2 =4.32; 20.08％,x2 =4.15 ; 25.08％,x2 =5.81 ; all P ＜0.05).There were no significant differences in the rates of calcium,magnesium,and vitamin D deficiencies between these two groups ( all P ＞ 0.05 ).The serum zinc [ ( 16.07 ± 3.56) vs.(23.24 ± 4.05) μmol/L,t =15.82,P ＜ 0.05 ],iron [ ( 19.89 ± 4.79) vs.(25.13 ± 5.07 ) μmol/L,t =6.65,P ＜ 0.05 ],and vitamin A levels [ ( 365.76 ±35.37 ) vs.(451.09 ± 32.16) μg/L,t =2.14,P ＜ 0.05 ] in the pneumonia group were significantly lower than those in the control group.The serum levels of calcium,magnesium,and 25-hydroxy vitamin D showed no significant difference between these two groups ( all P ＞ 0.05 ).Conclusion Zinc,iron,and/or vitamin A deficiencies are common among infant and children with pneumonia.
