CAJ | 학술논문

目的:探讨多发性硬化(Multiple sclerosis,MS)的临床和影像学表现.材料与方法:收集资料完整符合McDonald诊断标准的180例MS患者作为研究对象,按照国际MS中心制定的扫描序列进行扫描,分析MS主要临床特点、脑和脊髓病灶影像特点以及与临床残疾状态功能评分(Expanded disability status scale,EDSS)的相关性.结果:(1)本组MS患者以上呼吸道感染为主要诱因之一(27.78%),以肢体无力为最常见的症状(54.4%).(2)按照病灶受累的部位分类:单纯脑部受累45.56%,单纯脊髓受累29.44%,脑和脊髓均受累25%,三者之间的EDSS评分有统计学差别(P<0.05).(3)下颈髓和上胸髓最易受累,≤3个节段的病灶数占74.49%,累及1～2个节段脊髓病灶例数最多.结论:结合临床和MRI影像特征,有利于MS的诊断和监测病灶的发展.
목적:탐토다발성경화(Multiple sclerosis,MS)적림상화영상학표현.재료여방법:수집자료완정부합McDonald진단표준적180례MS환자작위연구대상,안조국제MS중심제정적소묘서렬진행소묘,분석MS주요림상특점、뇌화척수병조영상특점이급여림상잔질상태공능평분(Expanded disability status scale,EDSS)적상관성.결과:(1)본조MS환자이상호흡도감염위주요유인지일(27.78%),이지체무력위최상견적증상(54.4%).(2)안조병조수루적부위분류:단순뇌부수루45.56%,단순척수수루29.44%,뇌화척수균수루25%,삼자지간적EDSS평분유통계학차별(P<0.05).(3)하경수화상흉수최역수루,≤3개절단적병조수점74.49%,루급1～2개절단척수병조례수최다.결론:결합림상화MRI영상특정,유리우MS적진단화감측병조적발전.
Objective:To identify clinical and MRI images characteristics in patients with multiple sclerosis(MS).Methods:180 patients who fulfilled the MS diagnostic criteria of McDonald were selected to undergo MRI scans of the brain and spinal cord.The clinical characteristics and the MRI images of the brain and spinal cord were analyzed. The patient's neurological disability was assessed using the Kurtzke expanded disability states scale (EDSS) scores. Results:(1)The one of the main motivations is the upper respiratory tract infection(27.78%),and the most frequent onset symptom was weakness in one or more limbs(54.4%).(2)The patients with simple brain lesions were involved in 45.56%.followed by the spinal cords (29.44%),and both brain and spinal cord involvement in 25%.The EDSS scores were statistical differences among the patients with the simple brain involvement, simple spinal cord involvement, both brain and spinal cord involvements(P<0.05).(3)The lower cervical and upper thoracic spinal cords were easily involved,the length of cord lesions which were less than three vertebral segments was 74.49%,the 1～2 segments were the most frequent involved. Conclusion: The combination of clinical characteristics and conventional MRI can improve the diagnosis and monitor the progressive for patients with MS.