CAJ | 학술논문

目的了解新生儿感染的主要病原菌分布及耐药情况,为临床用药提供参考.方法对近2年新生儿病房送检的标本进行细菌培养及药敏试验.结果 2 172例送检标本培养出病原菌560例,阳性检出率为25.8%,560例阳性标本中检出病原菌583株,单独感染537例,混合感染23例.检出细菌中金黄色葡萄球菌占29.5%,肺炎克雷伯杆菌占22.0%,大肠埃希菌占17.0%.未发现耐万古霉素金黄色葡萄球菌,肺炎克雷伯杆菌及大肠埃希菌对亚胺培南敏感.结论新生儿感染仍以呼吸道感染为主,主要病原菌是金黄色葡萄球菌、肺炎克雷伯杆菌、大肠埃希菌,可见真菌混合感染.各病原菌对抗生索耐药率提高,给临床用药带来困难.
목적 료해신생인감염적주요병원균분포급내약정황,위림상용약제공삼고.방법 대근2년신생인병방송검적표본진행세균배양급약민시험.결과 2 172례송검표본배양출병원균560례,양성검출솔위25.8%,560례양성표본중검출병원균583주,단독감염537례,혼합감염23례.검출세균중금황색포도구균점29.5%,폐염극뢰백간균점22.0%,대장애희균점17.0%.미발현내만고매소금황색포도구균,폐염극뢰백간균급대장애희균대아알배남민감.결론 신생인감염잉이호흡도감염위주,주요병원균시금황색포도구균、폐염극뢰백간균、대장애희균,가견진균혼합감염.각병원균대항생색내약솔제고,급림상용약대래곤난.
Objective To know the etiology distribution and drug resistance in neonate, hope to provide the reference for clinic.Methods The identification and susceptibility of bacteria were detected by culture.Results 583 bacterial strains were identified from total 560 positive samples from 2127 neonate (25.8%).The infection neonates of single bacterial and complex bacterial were 537 and 23 respectively of all 560 patients.The ratio of staphylococcus aureus, klebsiella pneumoniae and E.coli were 29.5%,22.0% and 17.0% respectively in total 560 patients.Staphylococcus Aureus of Resistance to Vancomycin(VRSA) wasn't be found.Conclusion Respiratory tract infection is the major cause of infection in newborn, including staphylococcus aureus, klebsiella pneumoniae and E.coli.