中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
4期
447-449
,共3页
宫颈上皮内瘤样变%微波%妇科外科手术
宮頸上皮內瘤樣變%微波%婦科外科手術
궁경상피내류양변%미파%부과외과수술
Cervical intraepithelial neoplasia%Microwaves%Gynecologic surgical procedures
目的 探讨高频电波刀环切术(LEEP)对各级宫颈上皮内瘤变(CIN)、宫颈中重度炎症、宫颈HPV感染及宫颈息肉的诊治效果.方法 回顾性分析136例宫颈病变患者进行LEEP治疗后的随访资料.结果 LEEP术后病理级别升高者18例,占13.2%,降级者38例,占27.9%,术前术后诊断符合率为58.8%,差异有统计学意义(P<0.05).136例LEEP手术历时平均11 min,术中出血量平均15 ml,术后出血发生率2.2%,宫颈管粘连发生率1.5%.CIN治愈率为96%,病变残留率4%,复发率2%.术后第12个月,HPV转阴率86.7%,持续阳性率13.3%.HPV转阴率术后逐步上升.结论 LEEP术是治疗CIN的安全有效方法,对宫颈HPV清除具有较好疗效.
目的 探討高頻電波刀環切術(LEEP)對各級宮頸上皮內瘤變(CIN)、宮頸中重度炎癥、宮頸HPV感染及宮頸息肉的診治效果.方法 迴顧性分析136例宮頸病變患者進行LEEP治療後的隨訪資料.結果 LEEP術後病理級彆升高者18例,佔13.2%,降級者38例,佔27.9%,術前術後診斷符閤率為58.8%,差異有統計學意義(P<0.05).136例LEEP手術歷時平均11 min,術中齣血量平均15 ml,術後齣血髮生率2.2%,宮頸管粘連髮生率1.5%.CIN治愈率為96%,病變殘留率4%,複髮率2%.術後第12箇月,HPV轉陰率86.7%,持續暘性率13.3%.HPV轉陰率術後逐步上升.結論 LEEP術是治療CIN的安全有效方法,對宮頸HPV清除具有較好療效.
목적 탐토고빈전파도배절술(LEEP)대각급궁경상피내류변(CIN)、궁경중중도염증、궁경HPV감염급궁경식육적진치효과.방법 회고성분석136례궁경병변환자진행LEEP치료후적수방자료.결과 LEEP술후병리급별승고자18례,점13.2%,강급자38례,점27.9%,술전술후진단부합솔위58.8%,차이유통계학의의(P<0.05).136례LEEP수술력시평균11 min,술중출혈량평균15 ml,술후출혈발생솔2.2%,궁경관점련발생솔1.5%.CIN치유솔위96%,병변잔류솔4%,복발솔2%.술후제12개월,HPV전음솔86.7%,지속양성솔13.3%.HPV전음솔술후축보상승.결론 LEEP술시치료CIN적안전유효방법,대궁경HPV청제구유교호료효.
Objective To study the clinical effect of cervical loop electrosurgical excision procedure (LEEP) in diagnosis and treatment of cervical diseases (including cervical intraepithelial neoplasia of different grade, cervical erosion of moderate and severe degree, cervical with human papillomavims (HPV) infection and cervi-cal polyp) . Method The data of 136 cases with cervical disease treated by LEEP were analyzed retrospectively. Re-sult The postoperative diagnosis were upgraded in 18 cases (13.2%) ,and downgraded in 38cases (27.9 %) . The preoperative diagnosis of 80 cases (58.8 %) were in accordance with the postoperative ones. The difference was sig-nificant(P<0.05). The mean operative time was 11minutes, the mean bleeding volume was 15 ml. Postoperative bleeding of LEEP occurred in 2.2 % (3/136) patients. Postoperative cervical conglutination of LEEP occurred in 1. 5 % (2/136) patients. The cure rate of CIN was 96 % after LEEP. The residual CIN occurred in 4 patient (4 %). Recurrence CIN occurred in 2 patient (2 %). At 12th months after LEEP,the negative rate of HPV detection was 86. 7% and the persistent positive rate was 13.3%. The HPV clearance rate was increased gradually after LEEP. Conclu-sion LEEP was safe and effective for the treatment of the cervical disease and was a kind of good method to clear HPV infection in cervical.
