CAJ | 학술논문

目的分析胰腺神经内分泌肿瘤的外科治疗策略及影响预后的因素.方法回顾性分析1999年4月至2007年5月之间经手术治疗且病理证实的30例胰腺神经内分泌肿瘤患者的临床资料.根据WHO新的分级标准,对肿瘤大小、手术方式、病理类型与远期生存之间的关系进行分析.结果 30例患者中男性18例,女性12例;平均年龄54岁(28～78岁);5例失访,获得随访的25例患者中,良性20例、恶性5例;良、恶性组中位生存时间分别为74.8和33.8个月(X2=8.90,P=0.003).全组1、2、3、4、5年生存率分别为100%、100%、82.0%、82.0%、65.6%.结论胰腺内分泌肿瘤是一类比较少见的胰腺肿瘤.手术切除可获得良好的长期生存.新的WHO分型方法可以比较有效地预测肿瘤的预后.
목적 분석이선신경내분비종류적외과치료책략급영향예후적인소.방법 회고성분석1999년4월지2007년5월지간경수술치료차병리증실적30례이선신경내분비종류환자적림상자료.근거WHO신적분급표준,대종류대소、수술방식、병리류형여원기생존지간적관계진행분석.결과 30례환자중남성18례,녀성12례;평균년령54세(28～78세);5례실방,획득수방적25례환자중,량성20례、악성5례;량、악성조중위생존시간분별위74.8화33.8개월(X2=8.90,P=0.003).전조1、2、3、4、5년생존솔분별위100%、100%、82.0%、82.0%、65.6%.결론 이선내분비종류시일류비교소견적이선종류.수술절제가획득량호적장기생존.신적WHO분형방법가이비교유효지예측종류적예후.
Objective To analyze the surgical treatment strategy and prognostic factors of pancreatic neuroendocrine tumor. Methods The clinical data of 30 patients who underwent pancreatic surgery in our department from April, 1999 to May, 2007 were retrospectively reviewed. According to the new WHO classification system, factors possibly influence the long term survival, such as tumor size, operation types, pathological types, were analyzed. Results There were 18 males and 12 females, with a mean age of 54 years old (28 ～ 78 years old). Five patients were lost in follow up. Among 25 patients who were completely followed, 20 cases were benign and other 5 were malignant, the median survival time of benign and malignant group was 74.8 months and 33.8 months, respectively (X2 = 8.90, P = 0.003). Overall 1, 2, 3, 4, 5-year survival rates were 100%, 100%, 82. 0%, 82. 0%, 65. 6%, respectively. Conclusions Pancreatic neuroendocrine tumor was a rare type of tumor of the pancreas with a good prognosis if surgically resected. The new classification method was effective in predicting the prognosis.