中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2011年
10期
1014-1017
,共4页
屈光参差%高度近视%角膜滞后性%眼反应分析仪
屈光參差%高度近視%角膜滯後性%眼反應分析儀
굴광삼차%고도근시%각막체후성%안반응분석의
Anisometropia%High myopia%Corneal hysteresis%ORA
目的 分析和研究近视性的高度屈光参差眼屈光参数及角膜生物学参数的差异性.方法 对23名近视性的高度屈光参差患者(双眼等效球镜SE差≥6.00D),用眼反应分析仪(Ocular Response Analyzer,ORA)测量角膜滞后性(Corneal Hyteresis,CH),用改进的光学相干断层扫描仪(OCT-3)测量中央角膜厚度(CCT),用IOL-Master测量角膜曲率(mean K)及眼轴长度(AL).统计处理采用配对t检验和多元线性回归分析.结果 近视程度高度眼平均AL(28.34±1.10)mm,低度眼平均AL( 24.53±0.70)mm,差异有统计学意义(P＜0.01).双眼角膜平均曲率K差异无统计学意义(P＞0.05).双眼CCT差异无统计学意义(P＞0.05).近视程度高度眼CH平均值(10.00±1.61 )mm Hg,低度眼CH平均值( 10.96±1.38)mm Hg,双眼CH差异有统计学意义(P＜0.01)；高度眼CH与眼轴和角膜厚度相关(P＜0.05).结论 相同基因及环境下,高度近视眼的CH显著下降,角膜无明显变薄,提示眼轴的过度增长可能会导致角膜的微观结构改变,引起角膜的生物力学性能改变.
目的 分析和研究近視性的高度屈光參差眼屈光參數及角膜生物學參數的差異性.方法 對23名近視性的高度屈光參差患者(雙眼等效毬鏡SE差≥6.00D),用眼反應分析儀(Ocular Response Analyzer,ORA)測量角膜滯後性(Corneal Hyteresis,CH),用改進的光學相榦斷層掃描儀(OCT-3)測量中央角膜厚度(CCT),用IOL-Master測量角膜麯率(mean K)及眼軸長度(AL).統計處理採用配對t檢驗和多元線性迴歸分析.結果 近視程度高度眼平均AL(28.34±1.10)mm,低度眼平均AL( 24.53±0.70)mm,差異有統計學意義(P＜0.01).雙眼角膜平均麯率K差異無統計學意義(P＞0.05).雙眼CCT差異無統計學意義(P＞0.05).近視程度高度眼CH平均值(10.00±1.61 )mm Hg,低度眼CH平均值( 10.96±1.38)mm Hg,雙眼CH差異有統計學意義(P＜0.01)；高度眼CH與眼軸和角膜厚度相關(P＜0.05).結論 相同基因及環境下,高度近視眼的CH顯著下降,角膜無明顯變薄,提示眼軸的過度增長可能會導緻角膜的微觀結構改變,引起角膜的生物力學性能改變.
목적 분석화연구근시성적고도굴광삼차안굴광삼수급각막생물학삼수적차이성.방법 대23명근시성적고도굴광삼차환자(쌍안등효구경SE차≥6.00D),용안반응분석의(Ocular Response Analyzer,ORA)측량각막체후성(Corneal Hyteresis,CH),용개진적광학상간단층소묘의(OCT-3)측량중앙각막후도(CCT),용IOL-Master측량각막곡솔(mean K)급안축장도(AL).통계처리채용배대t검험화다원선성회귀분석.결과 근시정도고도안평균AL(28.34±1.10)mm,저도안평균AL( 24.53±0.70)mm,차이유통계학의의(P＜0.01).쌍안각막평균곡솔K차이무통계학의의(P＞0.05).쌍안CCT차이무통계학의의(P＞0.05).근시정도고도안CH평균치(10.00±1.61 )mm Hg,저도안CH평균치( 10.96±1.38)mm Hg,쌍안CH차이유통계학의의(P＜0.01)；고도안CH여안축화각막후도상관(P＜0.05).결론 상동기인급배경하,고도근시안적CH현저하강,각막무명현변박,제시안축적과도증장가능회도치각막적미관결구개변,인기각막적생물역학성능개변.
Objective To investigate the differences of refractive index and corneal biological parameter in high myopic anisometropia.Methods Twenty three subjects who suffered anisometropia (spherical equivalent ≥6.00 D) were selected.For each subject,corneal hysteresis (CH) was measured by ORA (Ocular Response Analyzer),central corneal thickness (CCT) was measured by OCT,average keratometer value (mean K) and ocular axial length (AL) were measured by Zeiss IOL-Master,the results were tested by paired t-test and multiple linear regression.Result The differences of mean K,CCT for two eyes were not significant (P ＞0.05).Mean AL was (28.34± 1.10) mm (SD) in high myopic eyes compared with (24.53± 0.70) mm in the fellow eye,the difference was statistically significant (P ＜0.0001).The mean hysteresis in high myopic eyes and the fellow eyes was (10.00± 1.61)mmHg and (10.96± 1.38) mmHg,respectively; the difference was statistically significant (P ＜0.0001).The relationship between CH and AL and CCT was statistically significant (P ＜0.05).Conclusions Under the same gene and environment,the corneal hysteresis value is significantly lower in high myopia,which has no thinner cornea.It may be due to the change in cornea microstructure as a result of axial abnormal elongation.
