中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2010年
14期
8-9,11
,共3页
陈大顺%袁争百%韩宏华%苏振琪
陳大順%袁爭百%韓宏華%囌振琪
진대순%원쟁백%한굉화%소진기
总胆固醇%低密度脂蛋白%血清脂蛋白(a)%甘油三酯%冠心病
總膽固醇%低密度脂蛋白%血清脂蛋白(a)%甘油三酯%冠心病
총담고순%저밀도지단백%혈청지단백(a)%감유삼지%관심병
Total cholesterol%Low density lipoprotein cholesterol%Lipoprotein(a)%Triglyceride%Coronary heart disease
目的 探讨血清脂蛋白水平与冠心病患者冠状动脉病变的关系.方法 冠状动脉造影患者323例,分为冠心病组和正常对照组,其中根据冠状动脉病变狭窄程度分为轻度、中度、重度狭窄组,根据冠状动脉病变范围分为单支病变组、双支病变组和多支病变组.分别测定其血清脂蛋白、总胆固醇、低密度脂蛋白、甘油三酯水平.结果 冠心病组血清脂蛋白、总胆固醇、低密度脂蛋白、甘油三酯水平明显高于正常对照组.其中血清脂蛋白、总胆固醇和低密度脂蛋白水平与冠状动脉病变呈正相关;双支及多支病变组明显高于对照组和单支病变组(P<0.01),中度狭窄和重度狭窄组明显高于对照组和轻度病变组(P<0.01).结论 血清脂蛋白、总胆固醇和低密度脂蛋白能够反映冠状动脉的病变情况,其水平随冠状动脉病变范围及病变程度的加重而升高,可作为预测冠状动脉病变的一个因素.
目的 探討血清脂蛋白水平與冠心病患者冠狀動脈病變的關繫.方法 冠狀動脈造影患者323例,分為冠心病組和正常對照組,其中根據冠狀動脈病變狹窄程度分為輕度、中度、重度狹窄組,根據冠狀動脈病變範圍分為單支病變組、雙支病變組和多支病變組.分彆測定其血清脂蛋白、總膽固醇、低密度脂蛋白、甘油三酯水平.結果 冠心病組血清脂蛋白、總膽固醇、低密度脂蛋白、甘油三酯水平明顯高于正常對照組.其中血清脂蛋白、總膽固醇和低密度脂蛋白水平與冠狀動脈病變呈正相關;雙支及多支病變組明顯高于對照組和單支病變組(P<0.01),中度狹窄和重度狹窄組明顯高于對照組和輕度病變組(P<0.01).結論 血清脂蛋白、總膽固醇和低密度脂蛋白能夠反映冠狀動脈的病變情況,其水平隨冠狀動脈病變範圍及病變程度的加重而升高,可作為預測冠狀動脈病變的一箇因素.
목적 탐토혈청지단백수평여관심병환자관상동맥병변적관계.방법 관상동맥조영환자323례,분위관심병조화정상대조조,기중근거관상동맥병변협착정도분위경도、중도、중도협착조,근거관상동맥병변범위분위단지병변조、쌍지병변조화다지병변조.분별측정기혈청지단백、총담고순、저밀도지단백、감유삼지수평.결과 관심병조혈청지단백、총담고순、저밀도지단백、감유삼지수평명현고우정상대조조.기중혈청지단백、총담고순화저밀도지단백수평여관상동맥병변정정상관;쌍지급다지병변조명현고우대조조화단지병변조(P<0.01),중도협착화중도협착조명현고우대조조화경도병변조(P<0.01).결론 혈청지단백、총담고순화저밀도지단백능구반영관상동맥적병변정황,기수평수관상동맥병변범위급병변정도적가중이승고,가작위예측관상동맥병변적일개인소.
Objective To investigate the possible relationship between the serum LP(a) and coronary artery changes in patients with coronary heart disease (CHD). Methods Coronary angiography (CAG) was performed in 323 patients. The patients were divided into CHD group and control group. The serum levels of lipids were measured. According to the coronary number of stenosis, CHD group was further divided into 1-vessel group, 2-vessel group and 3-vessel group according to the degree of coronary lesion, CHD group was further divided into light stenosis group, moderate stenosis group and severe stenosis group. Results The levels of total cholesterol (TC),LP(a),LDL-C and triglyceride (TG) in CHD patients were significant higher than those in the control group. The serum levels of TC,LP(a) and LDL-C were significantly related to CHD (P<0.01).The serum levels of TC,LP(a) and LDL-C were higher in the 2-vessel group and 3-vessel group than that in the control group and 1-vessel group (P<0.01).The serum levels of TC,LP(a) and LDL-C were higher in the moderate stenosis group, severe stenosis group than that in the control group and light stenosis group(P<0.01). Conclusions The increasing of TC, LP(a) and LDL-C are associated with the stenosis degrees and lesion degrees of coronary artery in patients with CHD which indicated that TC,LP(a) and LDL-C have clinical significance for evaluating the change of degree of coronary artery lesion.
