抗肿瘤活性四氢异喹啉生物碱全合成研究进展
항종류활성사경이규람생물감전합성연구진전
Synthetic Progress of the Tetrahydroisoquinoline Antitumor Alkaloids
  • 万方数据
    有机化学 유궤화학
    CHINESE JOURNAL OF ORGANIC CHEMISTRY
    2010年 3期 317-329 ,共13页

    廖祥伟%董文芳%刘伟%陈世智%刘站柱

    료상위%동문방%류위%진세지%류참주

    四氢异喹啉生物碱%Renieramycins%Ecteinascidins%Quinocarcin%全合成 四氫異喹啉生物堿%Renieramycins%Ecteinascidins%Quinocarcin%全閤成
    사경이규람생물감%Renieramycins%Ecteinascidins%Quinocarcin%전합성
    tetrahydroisoquinoline alkaloid%renieramycin%ecteinascidin%quinocarcin%total synthesis
    综述了近年来抗肿瘤活性四氢异喹啉生物碱Renieramycin,Ecteinascidin和Quinocarcin的全合成研究进展,对其构环顺序和方法进行了分析,对部分合成路线的优缺点进行了讨论.
    종술료근년래항종류활성사경이규람생물감Renieramycin,Ecteinascidin화Quinocarcin적전합성연구진전,대기구배순서화방법진행료분석,대부분합성로선적우결점진행료토론.
    The recent advance in the total synthesis of the tetrahydroisoquinoline alkaloids is reviewed, in-cluding renieramycins, ecteinascidins and quinocarcin. The strategies and sequences to construct the skele-ton have been analyzed. Some advantages or limitations of the synthetic routes have also been discussed.
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