国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2011年
24期
3066-3069
,共4页
金黄色葡萄球菌%抗菌药物%耐药%敏感%合理用药
金黃色葡萄毬菌%抗菌藥物%耐藥%敏感%閤理用藥
금황색포도구균%항균약물%내약%민감%합리용약
Staphylococcus aureus%Antibacterial drugs%Drug resistance%Sensitive%Reasonable drug use
目的 了解我院金黄色葡萄球菌临床分离株对抗菌药物的耐药性及感染现状,以指导临床医生更科学合理用药.方法 收集我院2009年11月- 2011年9月间住院及门诊患者的标本,对分离出的108株金黄色葡萄球菌进行药敏试验.结果 对甲氧西林耐药的金黄色葡萄球菌(MRSA)有76株,占70.4％；对甲氧西林敏感的金黄色葡萄球菌(MSSA)有32株,占29.6％.菌株主要分离于痰液/咽拭子,占42.6％；其次是分离于脓液/创面,占36.1％；其他的菌株分离于阴道分泌物、血液、尿液和精液,占21.3％.金黄色葡萄球菌中MRSA对16种抗菌药物的耐药率最高的是青霉素和苯唑西林,均为100.0％,而MSSA仅对青霉素的耐药率较高,达83.2％,对其余15种药物的耐药率都低于50％.万古霉素、呋喃妥因、替考拉宁耐药率在两者均为0.结论 甲氧西林敏感金黄色葡萄球菌除了青霉素外对大多数的抗菌药物有较好的敏感性,而耐甲氧西林金黄色葡萄球菌的检出率仍然很高且多为多药耐药性.
目的 瞭解我院金黃色葡萄毬菌臨床分離株對抗菌藥物的耐藥性及感染現狀,以指導臨床醫生更科學閤理用藥.方法 收集我院2009年11月- 2011年9月間住院及門診患者的標本,對分離齣的108株金黃色葡萄毬菌進行藥敏試驗.結果 對甲氧西林耐藥的金黃色葡萄毬菌(MRSA)有76株,佔70.4％；對甲氧西林敏感的金黃色葡萄毬菌(MSSA)有32株,佔29.6％.菌株主要分離于痰液/嚥拭子,佔42.6％；其次是分離于膿液/創麵,佔36.1％；其他的菌株分離于陰道分泌物、血液、尿液和精液,佔21.3％.金黃色葡萄毬菌中MRSA對16種抗菌藥物的耐藥率最高的是青黴素和苯唑西林,均為100.0％,而MSSA僅對青黴素的耐藥率較高,達83.2％,對其餘15種藥物的耐藥率都低于50％.萬古黴素、呋喃妥因、替攷拉寧耐藥率在兩者均為0.結論 甲氧西林敏感金黃色葡萄毬菌除瞭青黴素外對大多數的抗菌藥物有較好的敏感性,而耐甲氧西林金黃色葡萄毬菌的檢齣率仍然很高且多為多藥耐藥性.
목적 료해아원금황색포도구균림상분리주대항균약물적내약성급감염현상,이지도림상의생경과학합리용약.방법 수집아원2009년11월- 2011년9월간주원급문진환자적표본,대분리출적108주금황색포도구균진행약민시험.결과 대갑양서림내약적금황색포도구균(MRSA)유76주,점70.4％；대갑양서림민감적금황색포도구균(MSSA)유32주,점29.6％.균주주요분리우담액/인식자,점42.6％；기차시분리우농액/창면,점36.1％；기타적균주분리우음도분비물、혈액、뇨액화정액,점21.3％.금황색포도구균중MRSA대16충항균약물적내약솔최고적시청매소화분서서림,균위100.0％,이MSSA부대청매소적내약솔교고,체83.2％,대기여15충약물적내약솔도저우50％.만고매소、부남타인、체고랍저내약솔재량자균위0.결론 갑양서림민감금황색포도구균제료청매소외대대다수적항균약물유교호적민감성,이내갑양서림금황색포도구균적검출솔잉연흔고차다위다약내약성.
Objective To instruct clinicians to prescribe medications more logically by investigating the antibiotic resistance and current infection status of staphylococcus aureus isolates.Methods Drug sensitivity testing was conducted in 108 staphylococcus aureus stains isolated from our hospital during the period of November 2009 to September 2011.Results 76 of 108 (70.4％) strains were methicillin-resistant staphylo-coccus aureus,while 32 (29.6％) were methicillin- sensitive.The strains (43A％) were mainly isolated from sputum or throat swab,and 35.9％ from pus or wound.21.7％ of the strains were isolated from vaginal discharges,blood,urine,and semen.The highest rate of staphylococcus aureus MRSA to 16 kinds of antimicrobial resistance was penicillin and oxacillin both acounted for 100.0％,and penicillin-resistant MSSA only the high rate for 83.2％,other 15 drug resistance rates were low at 50％.Vancomycin,nitrofurantoin,teicoplanin resistance rates in both were 0.Conclusions methieillin-sensitive Staphylococcus aureus have good sensitivity for most of the antibiotics in addition to penicillin,and methicillin-resistant Staphylococcus aureus detection rate is still high and more for multi-drug resistance.
