CAJ | 학술논문

目的初步探讨实时组织弹性成像在前列腺素E2(PGE2)诱导的兔骨骼肌炎症中的应用价值.方法 20只新西兰大白兔右后肢注射PGE2建立肌肉炎症模型;每周注射1次,共5周,采用自身对照.注射后1、2、5周弹性成像扫查,将弹性图像同病理结果对照.结果 1、2、5周,注射侧同对侧比较差异均具有统计学意义(P<0.05);1、2周注射侧比较差异不具有统计学意义(P>0.05); 1、2周同5周注射侧比较差异具有统计学意义(P<0.05).结论实时组织弹性成像较二维超声能早期发现病变,对肌肉炎症的早期诊断有一定价值.
목적 초보탐토실시조직탄성성상재전렬선소E2(PGE2)유도적토골격기염증중적응용개치.방법 20지신서란대백토우후지주사PGE2건립기육염증모형;매주주사1차,공5주,채용자신대조.주사후1、2、5주탄성성상소사,장탄성도상동병리결과대조.결과 1、2、5주,주사측동대측비교차이균구유통계학의의(P<0.05);1、2주주사측비교차이불구유통계학의의(P>0.05); 1、2주동5주주사측비교차이구유통계학의의(P<0.05).결론 실시조직탄성성상교이유초성능조기발현병변,대기육염증적조기진단유일정개치.
Objective To evaluate real-time tissue elastography(RTE)on skeletal muscle inflammation induced by injection prostaglandin E2 (PGE2) in rabbits.Methods New Zealand white rabbits (n=20)were injected in right hind with PGE2 to establish inflammation models.Intramuscular injections were received weekly five times altogether.The contralateral was used as the control.The scanning was performed 1 week,2 weeks,5 weeks after injection.Images were in contrast with pathological results.Results 1 week,2 weeks and 5 weeks later,the differences between injection side and normal side were statistically significant(P<0.05).The difference between 1st and 5th week,2nd and 5th week were statistically significant(P<0.05).There was no significantly statistical difference between 1st and 2nd week(P<0.05).Conclusions RTE can find changes earlier than two-dimensional ultrasound in detection lesions,and provide help for improving the early diagnosis of skeletal muscle inflammation.