CAJ | 학술논문

目的探讨重度血小板减少症( sever thrombocytopenia,STP)对狼疮合并妊娠患者妊娠结局、产科并发症影响.方法对2006至201 1年收治的11例妊娠合并SLE性STP患者临床资料进行回顾性分析.结果 49例妊娠合并狼疮患者中,重度血小板减少(血小板低于40× 109/L)11例(中位数为28×109/L,范围为5～38×109/L).STP主要发生在妊娠晚期,常常合并多脏器损害.该组病例中4例胎儿丢失(包括治疗性引产3例.治疗性流产1例),余7例活产,其中早产儿5例,低体重儿4例,新生儿体重中位数为2212 9.结论 SLE相关的STP患者全身系统性病变严重,经过及时处理,在严密的围产期监测下,注意防治妊娠并发症,可获得较好的妊娠结局.
목적 탐토중도혈소판감소증( sever thrombocytopenia,STP)대랑창합병임신환자임신결국、산과병발증영향.방법 대2006지201 1년수치적11례임신합병SLE성STP환자림상자료진행회고성분석.결과 49례임신합병랑창환자중,중도혈소판감소(혈소판저우40× 109/L)11례(중위수위28×109/L,범위위5～38×109/L).STP주요발생재임신만기,상상합병다장기손해.해조병례중4례태인주실(포괄치료성인산3례.치료성유산1례),여7례활산,기중조산인5례,저체중인4례,신생인체중중위수위2212 9.결론 SLE상관적STP환자전신계통성병변엄중,경과급시처리,재엄밀적위산기감측하,주의방치임신병발증,가획득교호적임신결국.
Objective To investigate the effect of severe thrombocytopenia ( STP ) on pregnancy outcomes andobstetric complications in pregnant women with systemic lupus erythematosus ( SLE ).Methods The clinical dats on 11pregnant women with SLE-associated STP who had treated during the period of 2006 to 2011 were analyzed retrospectively.Results 11 of 49 pregnant women with SLE met the criteria for platelet count of less than 40× 109/L,with a median count of 21 × 109/L,ranging from 5 to 38× 109/L.STP mainly occurred in the third trimester,which was always complicated with multiple organ damage.Cesarean sections were performed in all patients.Fetal loss occurred in 4 women,premature labor in 5,and low neonatal weight in 4.The median neonatal weight was 2212 g.ConCltsions Even though the systemic symptoms were severe,the women with thrombocytopenia induced by lupus have a better pregnancy outcome under the conditions of proper treatment and close supervision during the perinatal period.