中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
7期
876-878
,共3页
股骨转子间骨折%低分子肝素%深静脉血栓
股骨轉子間骨摺%低分子肝素%深靜脈血栓
고골전자간골절%저분자간소%심정맥혈전
Geriatric intertrochanteric femur fracture%Heparin low-molecular-weight%Deep venous thrombosis
目的 探讨老年人股骨转子间骨折围手术期下肢深静脉血栓(DVT)的发生率及应用低分子肝素顶防DVT的有效性和安全性.方法 对2005年7月至2011年5月收治的65岁以上的179例股骨转子间骨折患者进行对照研究,完全随机分成2组,观察组106例患者腹壁皮下注射低分子肝素进行抗凝预防,对照组73例不采用任何预防方法.对比2组失血量及术后下肢DVT发生率的情况.结果 观察组与对照组失血量差异无统计学意义[观察组:(565±155)ml;对照组:(560±170)ml,P>0.05].2组患者术后下肢DVT发生率差异有统计学意义[观察组:12.3% (13/106);对照组:32.9%( 24/60),P<0.05].结论 低分子肝素可以有效预防老年人股骨转子间骨折术后DVT的发生,同时对于已发生的DVT有良好的治疗效果.
目的 探討老年人股骨轉子間骨摺圍手術期下肢深靜脈血栓(DVT)的髮生率及應用低分子肝素頂防DVT的有效性和安全性.方法 對2005年7月至2011年5月收治的65歲以上的179例股骨轉子間骨摺患者進行對照研究,完全隨機分成2組,觀察組106例患者腹壁皮下註射低分子肝素進行抗凝預防,對照組73例不採用任何預防方法.對比2組失血量及術後下肢DVT髮生率的情況.結果 觀察組與對照組失血量差異無統計學意義[觀察組:(565±155)ml;對照組:(560±170)ml,P>0.05].2組患者術後下肢DVT髮生率差異有統計學意義[觀察組:12.3% (13/106);對照組:32.9%( 24/60),P<0.05].結論 低分子肝素可以有效預防老年人股骨轉子間骨摺術後DVT的髮生,同時對于已髮生的DVT有良好的治療效果.
목적 탐토노년인고골전자간골절위수술기하지심정맥혈전(DVT)적발생솔급응용저분자간소정방DVT적유효성화안전성.방법 대2005년7월지2011년5월수치적65세이상적179례고골전자간골절환자진행대조연구,완전수궤분성2조,관찰조106례환자복벽피하주사저분자간소진행항응예방,대조조73례불채용임하예방방법.대비2조실혈량급술후하지DVT발생솔적정황.결과 관찰조여대조조실혈량차이무통계학의의[관찰조:(565±155)ml;대조조:(560±170)ml,P>0.05].2조환자술후하지DVT발생솔차이유통계학의의[관찰조:12.3% (13/106);대조조:32.9%( 24/60),P<0.05].결론 저분자간소가이유효예방노년인고골전자간골절술후DVT적발생,동시대우이발생적DVT유량호적치료효과.
Objective To find out the postoperative deep venous thrombosis(DVT) incidence in geriatric patients undergoing intertrochanteric femoral fractures surgery,and to evaluate the effectiveness and safety of low-molecular-weight heparin in the prevention of DVT.Methods From July 2005 to May 2011,179 geriatric patients with intertrochanteric femoral fractures treated with operation were divided into prophylaxis group and control group randomly.106 in the observation group and 73 in the control group.The observation group comprised 48 males and 58 females.The male patients included 19 cases proximal femoral nail(PFN),and 29 cases dynamic hip screw(DHS).The female patients included 21 cases PFN,and 37 cases DHS.In the control group,30 cases were male,43 cases were femal.The male patients included 11 cases PFN,and 19 eases DHS.The female patients included 12cases PFN,and 31 cases DHS.Results There were no significant changes between intra and postoperative bleeding in all the patients.In the observation group,13 patients had a DVT rate of 12.6%(13/106).In the control group,DVT occurred in 24 cases with an incidence of 32.9%(24/73).A significant difference in DVT incidence was found between these two groups.Conclusion Low-molecular-weight heparin can effectively reduce the incidence of DVT after intertrochanteric femoral fractures operation and has a good result in treating DVT.