CAJ | 학술논문

目的探讨在体肝脏3.0T单体素PRESS序列质子MRS自动匀场线宽(LW)和抑水率(WS)的信度及二者的相关性.方法采用GE Signa Excite HD 3.0T超导MR扫描仪,8通道相控阵线圈.1H-MRS采集参数为TR/TE 1500/30 ms,NSA 64,VOI 2 cm×2 cm×2 cm.波谱常规预扫描,记录LW和WS后进行波谱采集,然后重复执行一次得到另外一组LW及WS数据共计38组.计算两次LW和WS组内相关系数(ICC)、变异系数(CV)及两次重复测量结果之间的显著性,并对LW和WS行等级相关分析. 结果①前后两次波谱常规预扫描LW和WS的ICC分别为0.862、0.961(P均<0.0001);CV分别为0.20、0.18、0.09、0.08.两次LW(t=1.106, P=0.276)和WS(t=-1.349, P=0.186)差异均无统计学意义.②前后两次LW和WS相关系数为-0.659,-0.485(P均<0.0001). 结论 ①在体肝脏单体素3.0T质子波谱自动匀场与抑水信度较好,匀场与抑水效果差者相同部位重复进行匀场与抑水达到较好效果的预期成功率低.重复测量时匀场线宽的变异程度较抑水率大.②匀场效果与抑水效果呈中等程度相关,匀场效果好的更容易达到良好的抑水,从而有可能在采集中得到高分辨的可析性波谱.
목적 탐토재체간장3.0T단체소PRESS서렬질자MRS자동균장선관(LW)화억수솔(WS)적신도급이자적상관성.방법 채용GE Signa Excite HD 3.0T초도MR소묘의,8통도상공진선권.1H-MRS채집삼수위TR/TE 1500/30 ms,NSA 64,VOI 2 cm×2 cm×2 cm.파보상규예소묘,기록LW화WS후진행파보채집,연후중복집행일차득도령외일조LW급WS수거공계38조.계산량차LW화WS조내상관계수(ICC)、변이계수(CV)급량차중복측량결과지간적현저성,병대LW화WS행등급상관분석. 결과①전후량차파보상규예소묘LW화WS적ICC분별위0.862、0.961(P균<0.0001);CV분별위0.20、0.18、0.09、0.08.량차LW(t=1.106, P=0.276)화WS(t=-1.349, P=0.186)차이균무통계학의의.②전후량차LW화WS상관계수위-0.659,-0.485(P균<0.0001). 결론 ①재체간장단체소3.0T질자파보자동균장여억수신도교호,균장여억수효과차자상동부위중복진행균장여억수체도교호효과적예기성공솔저.중복측량시균장선관적변이정도교억수솔대.②균장효과여억수효과정중등정도상관,균장효과호적경용역체도량호적억수,종이유가능재채집중득도고분변적가석성파보.
Objective To assess the reliability of auto-shimming line width (LW) and water suppression rate (WS), and the correlation between them. Methods GE Signa Excite HD 3.0T system and eight-channel torso phased-array coils with PRESS sequence were performed in 38 volunteers. Liver spectra were collected with TR of 1500 ms, TE of 30 ms, VOI of 2 cm×2 cm×2 cm, NSA of 64 times. Spectroscopy routine auto-shimming pre-scanning program was executed and the values of LW and WS were recorded. Then another spectroscopy routine auto-shimming pre-scanning program was performed repeatedly and 38 groups of data were obtained totally. Intra-class correlation coefficients (ICC), coefficient of variation (CV) and significance test were conduced on 38 groups of LW and WS data. Spearman rank correlation analysis was used to assess the correlation of LW and WS. Results ①The ICC of LW and WS was 0.862 and 0.961 (both P＜0.0001), respectively, while the value of CV was 0.20, 0.18, 0.09 and 0.08, respectively. Significant difference was not observed; ②The value of correlation coefficient was -0.659, -0.485 (both P＜0.0001), respectively. Conclusion ①The reliability is excellent for in vivo liver 3.0T 1H-MRS and WS appears relatively stable; ②Indexes of LW correlate with WS moderately, and it seems the smaller the value of LW is, the easier to achieve higher WS.