中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2012年
4期
299-302
,共4页
王月娇%吴芹%杨丽琛%张晓蕊%曾超美%杨晓光%杜军保%刘捷
王月嬌%吳芹%楊麗琛%張曉蕊%曾超美%楊曉光%杜軍保%劉捷
왕월교%오근%양려침%장효예%증초미%양효광%두군보%류첩
母乳喂养%婴儿%铁,膳食%贫血
母乳餵養%嬰兒%鐵,膳食%貧血
모유위양%영인%철,선식%빈혈
Breast feeding%Infants%Iron,dietary%Anemia
目的 研究母乳喂养婴儿从4月龄开始进行为期2个月的预防性铁补充对其铁营养状况的影响.方法 将123名4月龄母乳喂养的婴儿按照简单随机化方法分为补铁组(63名)、对照组(60名),补铁组进行为期2个月的小剂量补铁(每大1 mg/kg),对照组不予干预.采集6月龄时静脉血测定C反应蛋白和各项铁营养状况指标,并定期监测其生长发育指标,比较6月龄男婴和女婴各项铁营养状况指标水平.结果 2个月的小剂量预防性补铁实验后,补铁组和对照组分别有26、34名婴儿完成随访,补铁组婴儿血红蛋白增长的中位数(95％CI值)为5.5(7.0～13.0)g/L,对照组为0.0(-9.0～15.0)g/L,补铁组血红蛋白增长高于对照组(u=-2.326,P＜0.05)；而两组婴儿其他铁营养状况指标及其体重、身长增长差异均无统计学意义(P值均＞0.05).6月龄时男婴和女婴平均红细胞体积分别为(75.89 ±3.34)、(77.20 ±3.17)fl(=4.73,P＜0.05),而其他铁营养状况指标性别差异均无统计学意义(P值均＞0.05).结论 4月龄婴儿小剂量预防性补充铁剂可增加其6月龄时血红蛋白水平,且对生长发育无明显影响.
目的 研究母乳餵養嬰兒從4月齡開始進行為期2箇月的預防性鐵補充對其鐵營養狀況的影響.方法 將123名4月齡母乳餵養的嬰兒按照簡單隨機化方法分為補鐵組(63名)、對照組(60名),補鐵組進行為期2箇月的小劑量補鐵(每大1 mg/kg),對照組不予榦預.採集6月齡時靜脈血測定C反應蛋白和各項鐵營養狀況指標,併定期鑑測其生長髮育指標,比較6月齡男嬰和女嬰各項鐵營養狀況指標水平.結果 2箇月的小劑量預防性補鐵實驗後,補鐵組和對照組分彆有26、34名嬰兒完成隨訪,補鐵組嬰兒血紅蛋白增長的中位數(95％CI值)為5.5(7.0～13.0)g/L,對照組為0.0(-9.0～15.0)g/L,補鐵組血紅蛋白增長高于對照組(u=-2.326,P＜0.05)；而兩組嬰兒其他鐵營養狀況指標及其體重、身長增長差異均無統計學意義(P值均＞0.05).6月齡時男嬰和女嬰平均紅細胞體積分彆為(75.89 ±3.34)、(77.20 ±3.17)fl(=4.73,P＜0.05),而其他鐵營養狀況指標性彆差異均無統計學意義(P值均＞0.05).結論 4月齡嬰兒小劑量預防性補充鐵劑可增加其6月齡時血紅蛋白水平,且對生長髮育無明顯影響.
목적 연구모유위양영인종4월령개시진행위기2개월적예방성철보충대기철영양상황적영향.방법 장123명4월령모유위양적영인안조간단수궤화방법분위보철조(63명)、대조조(60명),보철조진행위기2개월적소제량보철(매대1 mg/kg),대조조불여간예.채집6월령시정맥혈측정C반응단백화각항철영양상황지표,병정기감측기생장발육지표,비교6월령남영화녀영각항철영양상황지표수평.결과 2개월적소제량예방성보철실험후,보철조화대조조분별유26、34명영인완성수방,보철조영인혈홍단백증장적중위수(95％CI치)위5.5(7.0～13.0)g/L,대조조위0.0(-9.0～15.0)g/L,보철조혈홍단백증장고우대조조(u=-2.326,P＜0.05)；이량조영인기타철영양상황지표급기체중、신장증장차이균무통계학의의(P치균＞0.05).6월령시남영화녀영평균홍세포체적분별위(75.89 ±3.34)、(77.20 ±3.17)fl(=4.73,P＜0.05),이기타철영양상황지표성별차이균무통계학의의(P치균＞0.05).결론 4월령영인소제량예방성보충철제가증가기6월령시혈홍단백수평,차대생장발육무명현영향.
Objective To analyze the effects to iron status who were given preventive iron supplements for two months from when they were breast-fed to four-month-old.Methods A total of 123infants in four-month-old age who were breast-fed were randomly divided into iron supplementation group (63 cases) and control group (60 cases),iron supplementation group was supplied with low-dose iron ( 1 mg·kg-1·d -1 ) for two months with no intervention for control group.Blood samples were collected to test C reactive protein and iron status indicators in six-month-old age group infants,and the growth indices were measured and compared on the gender difference of iron status at 6 months.Results After 2 months of low-dose iron supplementation,the hemoglobin of iron supplementation group (26 cases) increased about 5.5 g/L while the control group ( 34 cases ) increased about 0.0 g/L ( median),95％ confidence intervals were -7.0 - 13.0 g/I.and - 9.0 - 15.0 g/L, respectively. The hemoglobin increase of iron supplementation group was higher than the control group, the difference was statistically significant (u =-2.326,P ＜ 0.05 ).The other iron nutritional status and the growth did not show any significant difference between iron supplementation group and control group ( all P values ＞ 0.05 ).At age 6 months,the MCV of the boys were (75.89 ± 3.34)fl,while the girls were (77.20 ± 3.17 )fl.The boys had lower values of MCV than the girls,and the gender difference was statistically significant (t =4.73,P ＜ 0.05 ).The other iron nutritional status did not show any significant gender difference ( all P values ＞ 0.05 ).Conclusion Low-dose iron supplementation of breast-fed infants at 4-month-old could increase the hemoglobin level when they were 6-month-old,and had no measurable side effect on growth.
