国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2011年
3期
275-278
,共4页
膀胱疾病%灌注,局部
膀胱疾病%灌註,跼部
방광질병%관주,국부
Bladder Diseases%Perfusion,Regional
目的 探讨膀胱灌注辣椒辣素类似物(Besiniferatoxin,RTX)与异搏定膀胱灌注治疗女性膀胱过度活动症(OAB)的临床效果.方法 将60例OAB患者随机分为实验组与对照组,实验组23例用0.5%利多卡因溶液40mL从导尿管注入膀胱,保留30min后全部排出,予以膀胱灌注辣椒辣素类似物(RTX)治疗;对照组23例用异搏定替代RTX,方法 同实验组.比较两种方法 处理的患者疗效自我评定结果、治疗前以及治疗后3个月的临床症状和尿动力学指标、副反应情况、随访1年的复发情况.结果治疗前与治疗后3个月的临床症状比较,实验组治疗前后有5组数值的差异有显著意义(P＜0.05);对照组有3组数值的差异有显著意义(P＜0.05).结论 相比异搏定,RTX单剂量膀胱灌注能更安全有效的改善女性OAB临床症状.
目的 探討膀胱灌註辣椒辣素類似物(Besiniferatoxin,RTX)與異搏定膀胱灌註治療女性膀胱過度活動癥(OAB)的臨床效果.方法 將60例OAB患者隨機分為實驗組與對照組,實驗組23例用0.5%利多卡因溶液40mL從導尿管註入膀胱,保留30min後全部排齣,予以膀胱灌註辣椒辣素類似物(RTX)治療;對照組23例用異搏定替代RTX,方法 同實驗組.比較兩種方法 處理的患者療效自我評定結果、治療前以及治療後3箇月的臨床癥狀和尿動力學指標、副反應情況、隨訪1年的複髮情況.結果治療前與治療後3箇月的臨床癥狀比較,實驗組治療前後有5組數值的差異有顯著意義(P＜0.05);對照組有3組數值的差異有顯著意義(P＜0.05).結論 相比異搏定,RTX單劑量膀胱灌註能更安全有效的改善女性OAB臨床癥狀.
목적 탐토방광관주랄초랄소유사물(Besiniferatoxin,RTX)여이박정방광관주치료녀성방광과도활동증(OAB)적림상효과.방법 장60례OAB환자수궤분위실험조여대조조,실험조23례용0.5%리다잡인용액40mL종도뇨관주입방광,보류30min후전부배출,여이방광관주랄초랄소유사물(RTX)치료;대조조23례용이박정체대RTX,방법 동실험조.비교량충방법 처리적환자료효자아평정결과、치료전이급치료후3개월적림상증상화뇨동역학지표、부반응정황、수방1년적복발정황.결과치료전여치료후3개월적림상증상비교,실험조치료전후유5조수치적차이유현저의의(P＜0.05);대조조유3조수치적차이유현저의의(P＜0.05).결론 상비이박정,RTX단제량방광관주능경안전유효적개선녀성OAB림상증상.
Objectives To study intravesical Resiniferatoxin(RTX)and Verapamil in treatment of female overactive bladder(OAB)clinical results.Methods 60 patients with OAB were randomly divided into experimental and control groups.In experimental group of 23 patients,40mL of 0.5% lidocaine solution infused into the bladder from the catheter,all reservations after 30min discharged,with RTX intravosical therapy.The control group of 23 patients were intravesed with Verapamil,as the experimental group.Compared two self-efficacy methods to assessing the results of the patients before treatment and 3 months after treatment,clinical symptoms and urodynmic indices,the two methods side effects of treatment condition,followed up for 1 year recurrence.Results Compared clinical symptoms,5 groups values were significant differences(P＜0.05)in experimental groups before and 3 months after treatment,it only 3 groups values in control groups(p＜0.05).Conclusions Compared to Verapamil,RTX single dose of intravesieal instillation can lessen female OAB symptoms more safely and effectivdy.
