中国行为医学科学
中國行為醫學科學
중국행위의학과학
2008年
12期
1086-1088
,共3页
连勇军%周曙%刘中华%吴燕
連勇軍%週曙%劉中華%吳燕
련용군%주서%류중화%오연
回返抑制%工作记忆容量%事件相关电位
迴返抑製%工作記憶容量%事件相關電位
회반억제%공작기억용량%사건상관전위
Backward inhibition%Working memory capacity%Event-related potential
目的 探究工作记忆容量(WMC)与回返抑制(BI)的相互关系,结合事件相关电位(ERP)时空模式考察BI产生的时间和相关脑区.方法 24名受试者先进行延迟匹配样本任务测量WMC,再行3种线索提示下的数字属性判断任务:质数或合数、奇数或偶数、大于5或小于5,受试者以左右手按键判断,ABA类型的重复序列或CBA类型的非重复序列分别构成测试与对照任务,同步记录ERP.对高低容量组各9人的行为数据和ERP分别进行统计分析.结果 24名受试者wMc的K分值为(4.13±1.02)分;高容量组BI效应显著高于低容量组(t(16)=2.345,P=0.032);正确率差异无显著性(t(16)=0.738,P=0.471).ERP的F值统计参数映像提示容量与任务的显著交互效应发生在-390~-370ms和250~290ms的额顶区.结论 BI效应受工作记忆容量影响,高容量者BI效应更大;回返抑制可能产生于线索(-390~-370ms)和刺激(250~290ms)评价两个阶段,相关脑区恰好同工作记忆涉及区域重叠.
目的 探究工作記憶容量(WMC)與迴返抑製(BI)的相互關繫,結閤事件相關電位(ERP)時空模式攷察BI產生的時間和相關腦區.方法 24名受試者先進行延遲匹配樣本任務測量WMC,再行3種線索提示下的數字屬性判斷任務:質數或閤數、奇數或偶數、大于5或小于5,受試者以左右手按鍵判斷,ABA類型的重複序列或CBA類型的非重複序列分彆構成測試與對照任務,同步記錄ERP.對高低容量組各9人的行為數據和ERP分彆進行統計分析.結果 24名受試者wMc的K分值為(4.13±1.02)分;高容量組BI效應顯著高于低容量組(t(16)=2.345,P=0.032);正確率差異無顯著性(t(16)=0.738,P=0.471).ERP的F值統計參數映像提示容量與任務的顯著交互效應髮生在-390~-370ms和250~290ms的額頂區.結論 BI效應受工作記憶容量影響,高容量者BI效應更大;迴返抑製可能產生于線索(-390~-370ms)和刺激(250~290ms)評價兩箇階段,相關腦區恰好同工作記憶涉及區域重疊.
목적 탐구공작기억용량(WMC)여회반억제(BI)적상호관계,결합사건상관전위(ERP)시공모식고찰BI산생적시간화상관뇌구.방법 24명수시자선진행연지필배양본임무측량WMC,재행3충선색제시하적수자속성판단임무:질수혹합수、기수혹우수、대우5혹소우5,수시자이좌우수안건판단,ABA류형적중복서렬혹CBA류형적비중복서렬분별구성측시여대조임무,동보기록ERP.대고저용량조각9인적행위수거화ERP분별진행통계분석.결과 24명수시자wMc적K분치위(4.13±1.02)분;고용량조BI효응현저고우저용량조(t(16)=2.345,P=0.032);정학솔차이무현저성(t(16)=0.738,P=0.471).ERP적F치통계삼수영상제시용량여임무적현저교호효응발생재-390~-370ms화250~290ms적액정구.결론 BI효응수공작기억용량영향,고용량자BI효응경대;회반억제가능산생우선색(-390~-370ms)화자격(250~290ms)평개량개계단,상관뇌구흡호동공작기억섭급구역중첩.
Objective To explore the relationship between backward inhibition (BI) effect and working memory capacity (WMC) and the mechanism of BI with spatio-temporal patterns of event-related potentials.Methods Twenty-four subjects firstly took the delayed match-to-sample task to determine WMC.Each subject was divided into either high or low capacity group.Afterwards subjects took tasks of the digit properties judgment with difrerent cues:prime or composite,odd or even, more or less than five.ERP and behavioral performances of ABAtype task sequence,CBA-type task sequence were analyzed respectively.Eighteen subjects entered the final analysis and distributed to the low and the hihg by their WMC evenly.Results The K-WMC mean score of 24 subjects was (4.13±1.02),and date from 18 subjects entered into statistical analysis.No significant difference of cosection rate was found between two groups (t(16)=0.738,P=0.471),except for the value of BI effect.The high WMC group had higher BI effect significantly (t(0.05,16)=2.345,P=O.032).Statistical parametric mapping of Fvalue of EBP suggested significant interactions between WMC and BI exist during two periods:from -390~ -370ms (before target) and from 250~290 ms and involve similar bilateral frontal and parietal lobes.Conclusion BI effect involved frontal and parietal network in both cue and stimulus evaluation,which overlapped with the brain regions of working memory.