中国临床营养杂志
中國臨床營養雜誌
중국림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2001年
2期
98-99
,共2页
曹丽萍%邓诗琳%高志刚%谢宇钢%梁彦辉
曹麗萍%鄧詩琳%高誌剛%謝宇鋼%樑彥輝
조려평%산시림%고지강%사우강%량언휘
目的分析rhGH对严重烧伤病人血糖及蛋白质代谢的影响。方法对24例应用rhGH严重烧伤病人的血清总蛋白、白蛋白及血糖升高发生率进行比较分析。并对同期未应用rhGH患者血糖及蛋白质的变化进行总结分析。结果严重烧伤病人应用rhGH后血清总蛋白、白蛋白较用药前明显升高，并高于同期对照组。伤后2周内血糖升高，特别伤后1周内明显升高，伤后2周内血糖升高发生率分别为52.38%、50.00%、20.00%。伤后一周内、二周内及二周后开始应用rhGH其血糖升高发生率分别为100%、50%、0%。结论严重烧伤病人应用rhGH能促进机体蛋白质合成，但伤后早期应用rhGH对血糖影响较大，伤后2周后应用rhGH是较合适的时机。
目的分析rhGH對嚴重燒傷病人血糖及蛋白質代謝的影響。方法對24例應用rhGH嚴重燒傷病人的血清總蛋白、白蛋白及血糖升高髮生率進行比較分析。併對同期未應用rhGH患者血糖及蛋白質的變化進行總結分析。結果嚴重燒傷病人應用rhGH後血清總蛋白、白蛋白較用藥前明顯升高，併高于同期對照組。傷後2週內血糖升高，特彆傷後1週內明顯升高，傷後2週內血糖升高髮生率分彆為52.38%、50.00%、20.00%。傷後一週內、二週內及二週後開始應用rhGH其血糖升高髮生率分彆為100%、50%、0%。結論嚴重燒傷病人應用rhGH能促進機體蛋白質閤成，但傷後早期應用rhGH對血糖影響較大，傷後2週後應用rhGH是較閤適的時機。
목적분석rhGH대엄중소상병인혈당급단백질대사적영향。방법대24례응용rhGH엄중소상병인적혈청총단백、백단백급혈당승고발생솔진행비교분석。병대동기미응용rhGH환자혈당급단백질적변화진행총결분석。결과엄중소상병인응용rhGH후혈청총단백、백단백교용약전명현승고，병고우동기대조조。상후2주내혈당승고，특별상후1주내명현승고，상후2주내혈당승고발생솔분별위52.38%、50.00%、20.00%。상후일주내、이주내급이주후개시응용rhGH기혈당승고발생솔분별위100%、50%、0%。결론엄중소상병인응용rhGH능촉진궤체단백질합성，단상후조기응용rhGH대혈당영향교대，상후2주후응용rhGH시교합괄적시궤。
Objective To investigate the influence of rhGH on blood sugar andprotein synthesis in severe burn patients. Methods 24 severe burn patients were enrolled in this study.The rhGH was administered subcutaneously in the dose of 0.2～0.25 IU/kg*d-1 at 10pm every day for 10 to 14 days.Serum total pertein,albumin and blood sugar concentrations were determined and analyzed before treatment with rhGH and after. Results Serum total protein and albumin levels were sygnificantly increased of the rhGH provided than before and placebo control in the same stage.The bolld sugar level was enhanced in 2 weeks after burn injury,especially in a week after burn injury.The incidences of hyperglycemia were 52.38% in 3 days after burn injury,50.00% in a week nd 20.00% in two weeks in severe burn patients.When rhGH was administered in a week,two weeks and more than two weeks after burn injury,the incidences of hyperglycemia were 100%,50% and 0% respectively. Conclusions The rhGH could promote protein synthesis in severe burn patients.The rhGH could cause blood sugar increasing in early stage after burn injury,so it was in good time that the rhGH was provided rof severe burn patients during more than two weeks after burn injury.
