CAJ | 학술논문

目的评价菲立磁增强MRI在肝脏实性占位性病变诊断中的应用价值。材料与方法对21例怀疑有肝脏局灶性占位病变患者行MR平扫及菲立磁增强MRI检查。扫描序列包括频率选择脂肪抑制及非脂肪抑制HASTE T2WI、True FISP T2*WI、频率选择脂肪抑制FLASH T1WI。比较增强前后T2WI及T2*WI病灶及肝脏的信噪比(SNR)及对比噪声比(CNR)；观察增强前后病灶数量及形态；结合MR平扫及增强MRI表现进行定性诊断。结果菲立磁增强T2WI及T2*WI肝脏信号强度较平扫明显下降，病灶与肝脏的CNR较平扫明显提高，差异具有统计学意义。结论菲立磁增强T2WI及T2*WI可明显提高肝脏实性占位性病灶的检出率。菲立磁增强T1WI在肝脏局灶性病变的定性诊断中具有潜在价值，有待于进一步开发与研究。
목적평개비립자증강MRI재간장실성점위성병변진단중적응용개치。재료여방법대21례부의유간장국조성점위병변환자행MR평소급비립자증강MRI검사。소묘서렬포괄빈솔선택지방억제급비지방억제HASTE T2WI、True FISP T2*WI、빈솔선택지방억제FLASH T1WI。비교증강전후T2WI급T2*WI병조급간장적신조비(SNR)급대비조성비(CNR)；관찰증강전후병조수량급형태；결합MR평소급증강MRI표현진행정성진단。결과비립자증강T2WI급T2*WI간장신호강도교평소명현하강，병조여간장적CNR교평소명현제고，차이구유통계학의의。결론비립자증강T2WI급T2*WI가명현제고간장실성점위성병조적검출솔。비립자증강T1WI재간장국조성병변적정성진단중구유잠재개치，유대우진일보개발여연구。
Objective　To evaluate Feridex (superparamagnetic iron oxide, SPIO) enhanced MRI in the diagnosis of hepatic focal solid lesions.　Materials and Methods　Plain and Feridex-enhanced MRI were performed in 21 patients with suspected focal hepatic lesions. The enhanced-MRI scanning started at 60min. After intravenous infusion of 10μmol/kg of Feridex. The effect of Feridex on signal intensity of the liver, CNR of lesion vs liver were assessed with quantitative analysis.　Results　Compared with plain scan, signal intensity of liver on Feridex-enhanced T2WI was significantly decreased and CNRs of lesion vs liver were significantly improved.　Conclusion　The defection of focal lesions in liver can be significantly with Feridex-enhanced T2WI and T2*WI. Feridex-enhanced T2WI is very useful for the diagnosis of focal hepatic lesions and Feridex-enhanced T1WI has potential for qualitative diagnosis of focal hepatic lesions.