CAJ | 학술논문

目的：探讨牙周洁治前后唾液中前列腺素(PGs)变化，分析牙周洁治与PGs的关系。方法：选慢性牙周炎(CP)患者19例、青少年牙周炎(JP)患者11例,牙龈炎和健康人各10例，用放射免疫测定法分析牙周洁治前后患者唾液中6-酮-前列腺素F1a(6-K-PGF1a)和前列腺素E2(ProstaglandinE2,PGE2)含量变化。结果：洁治后牙周炎组患者唾液中6-K-PGF1a和PGE2较治疗前明显降低，牙龈炎组患者唾液中6-k-PGF1a和PGE2含量较洁治前降低最明显，健康人组唾液中6-K-PGF1a和PGE2含量较治疗前轻度降低。洁治后CP组患者唾液中6-K-PGF1a和PGE2较治疗前明显降低,而对JP患者降低程度较CP明显降低。结论：牙周洁治对牙龈炎患者唾液中PGs降低程度最强，对牙周炎和健康人有一定降低作用,对JP患者降低程度最差。牙周洁治的作用机理可能与调节机体唾液中的PGs有密切关系。
목적：탐토아주길치전후타액중전렬선소(PGs)변화，분석아주길치여PGs적관계。방법：선만성아주염(CP)환자19례、청소년아주염(JP)환자11례,아간염화건강인각10례，용방사면역측정법분석아주길치전후환자타액중6-동-전렬선소F1a(6-K-PGF1a)화전렬선소E2(ProstaglandinE2,PGE2)함량변화。결과：길치후아주염조환자타액중6-K-PGF1a화PGE2교치료전명현강저，아간염조환자타액중6-k-PGF1a화PGE2함량교길치전강저최명현，건강인조타액중6-K-PGF1a화PGE2함량교치료전경도강저。길치후CP조환자타액중6-K-PGF1a화PGE2교치료전명현강저,이대JP환자강저정도교CP명현강저。결론：아주길치대아간염환자타액중PGs강저정도최강，대아주염화건강인유일정강저작용,대JP환자강저정도최차。아주길치적작용궤리가능여조절궤체타액중적PGs유밀절관계。
Objective:To study the relationship between periodontal scalingand the contents of 6-Keto-Prostaglandin F1a (6-K-PGF1a) and prostaglandin E2 (PGE2) in salivary with periodontal diseases.Methods:19 cases chronic periodontitis(CP)、11 cases juvenile periodontitis(JP)、10 cases gingivitis and 10 cases health were selected,and measured the contents of 6-K-PGF1a and PGE2 in saliva of each patient by radioimmunoassay and analyzing the difference between scaling before and scaling after.Results:The contents of 6-K-PGF1a and PGE2 in saliva of group periodontitis were more significant reduced after scaling.The contents of 6-K-PGF1a and PGE2 in saliva of group gingivitis after scaling were decreased more severely than before scaling.But that of group health decreased less after scaling.There was no significant difference between group gingivitis and group health.The contents of 6-K-PGF1a and PGE2 in saliva with CP after scaling were decreased more severely than before scaling,but that of JP were not.Conclusions:There were more decreased effects of periodontal scaling to the contents of PGs with different periodontal diseases,and the decreased effects to PGs of group gingivitis were bigger than others.And there were some decreased effects to group periodontitis and group health,and fewer effects to group JP.The mechanisms of scaling more related to the contents of PGs in saliva.