CAJ | 학술논문

目的观察5 Hz和20 Hz磁场对脑缺血损害的影响。方法采用左侧颈总动脉阻断致大鼠急性脑缺血，缺血后给予5 Hz和20 Hz的磁场刺激3 h或5 h。观察脑细胞的缺血性病理变化。结果锥体细胞和星形胶质细胞表现出不同的缺血性病理变化；对锥体细胞的缺血性损害5 Hz组轻于对照组和20 Hz组，而对星形胶质细胞则表现为5 Hz组的缺血性损害程度重于对照组和20 Hz组；20 Hz组的缺血性损害程度与对照组相似。结论不同频率的磁场对大鼠脑急性缺血性损害有不同的影响，磁场的频率效应可能与磁场作用机制及细胞的不同特性有关。
목적 관찰5 Hz화20 Hz자장대뇌결혈손해적영향。 방법 채용좌측경총동맥조단치대서급성뇌결혈，결혈후급여5 Hz화20 Hz적자장자격3 h혹5 h。관찰뇌세포적결혈성병리변화。 결과 추체세포화성형효질세포표현출불동적결혈성병리변화；대추체세포적결혈성손해5 Hz조경우대조조화20 Hz조，이대성형효질세포칙표현위5 Hz조적결혈성손해정도중우대조조화20 Hz조；20 Hz조적결혈성손해정도여대조조상사。 결론 불동빈솔적자장대대서뇌급성결혈성손해유불동적영향，자장적빈솔효응가능여자장작용궤제급세포적불동특성유관。
Objective To compare the effects of 5 Hz and 20 Hz magnetic field on cerebral ishemia in rats. Method After cerebral ischemia was produced by ligation of the left general carotid artery,rats were stimulated by magnetic fields of 5 Hz and 20 Hz respectively and pathological changes in neurocytes were observed. Result (1) Different pathological changes were observed in different cells;(2)The extent of damage of pyramidal cells was milder in 5 Hz magnetic field groups than those in the control group ,and the effect was not remarkable in the 20 Hz group;(3)The effect on astroglia was worse in 5 Hz group than that in control and 20 Hz group. Conclusion Magnetic field stimulation influences cerebral ischemic reaction with frequency-dependency.