CAJ | 학술논문

目的：比较血定安与血代两类药物对患者凝血功能的影响。方法：选择60例ASA(美国麻醉医师学会)1～2级手术患者随机分为两组(血定安组与血代组)。入室后采集静脉血测定凝血酶原时间、纤维蛋白酶定量、血小板计数、血球压积和血钙含量。分别输入血定安与血代1000ml后，再次于非输液侧采集静脉血，监测上述指标。结果：比较两类药物输液前后血球压积P<0.05，差异显著性。其余各项指标均在正常范围内变化。结论：输注血浆代用品后对凝血机制无明显影响，仅对血液有稀释作用。通过稀释血液，还能提高血液的运氧能力。
목적：비교혈정안여혈대량류약물대환자응혈공능적영향。방법：선택60례ASA(미국마취의사학회)1～2급수술환자수궤분위량조(혈정안조여혈대조)。입실후채집정맥혈측정응혈매원시간、섬유단백매정량、혈소판계수、혈구압적화혈개함량。분별수입혈정안여혈대1000ml후，재차우비수액측채집정맥혈，감측상술지표。결과：비교량류약물수액전후혈구압적P<0.05，차이현저성。기여각항지표균재정상범위내변화。결론：수주혈장대용품후대응혈궤제무명현영향，부대혈액유희석작용。통과희석혈액，환능제고혈액적운양능력。
Objective:To evaluate the effect of two plasma substitutes (Gelofusne and Hemaccd)on blood coagulation. Methods: 60 cases of undergo operation were randomized into two groups, and taken vein blood sample before and after the injection of the two blood substitutes, then testing the coagulation time, fibrinogenase concentration, the number of platelet, and the hematocrit, as well as the calcium content respectively. Results: The results showed that only the hemaocrit was higher than that of being injected the two blood substitutes. Other items had not changed obviously. Conclusion:The blood plasma substitutes have the effect of dilution blood,but don't influence the coagulation.