CAJ | 학술논문

报告21例融合性网状乳头瘤病,其中男13例,女8例.发病年龄9～27岁(平均17.7岁),病程1个月～7年.临床上皮损以躯干中部为著,为密集分布的灰褐色丘疹或斑片,相互间融合呈网纹状.真菌检查均为阴性.组织病理学表现为表皮呈"城垛样"平顶或呈锥状.治疗给予米诺环素50 mg每日2次口服,0.1%维A酸乳膏外涂.4周后皮损开始好转,8周后皮损明显缓解.
보고21례융합성망상유두류병,기중남13례,녀8례.발병년령9～27세(평균17.7세),병정1개월～7년.림상상피손이구간중부위저,위밀집분포적회갈색구진혹반편,상호간융합정망문상.진균검사균위음성.조직병이학표현위표피정"성타양"평정혹정추상.치료급여미낙배소50 mg매일2차구복,0.1%유A산유고외도.4주후피손개시호전,8주후피손명현완해.
Confluent and reticlated papillomatosis(CRP)was diagnosed in 21 patients between 2005 and 2008.Of whom,13 were males and 8 were females,mean age at the onset of skin eruptions was 17.7 years(range 9-27),with the disease course from 1 month to 7 years.Physical examination showed scaly brownish papules and patches on the trunks of them,syncretizing to reticulated appearence.Fungal microscopy and subsequent cultures were negative.The histopathologic features of CRP was an undulating overall profile of the hyperkeratosis,low-papillomatosis,and some acanthotic down-growth from the base of the interpapillary areas.Oral minocycline(50 mg twice daily)and topical tretinoin(0.1% cream)was prescribed.An improvement was found usually in 4 weeks and significant improvement in 8 weeks.