CAJ | 학술논문

建立了化妆品中15种挥发性有机溶剂残留的顶空气相色谱测定方法.样品经60 ℃、30 min静态顶空后,采用气相色谱-氢火焰离子化检测器进行检测,外标法定量.加标回收试验结果表明:15种挥发性有机溶剂残留平均回收率为62.8% ～116% ,相对标准偏差均小于5% .方法的检出限为0.09～0.68 mg/kg.该方法可有效克服基体干扰,一次进样可同时分离和测定化妆品中15种挥发性有机溶剂,准确灵敏,简单快速,适用于化妆品中挥发性有机溶剂残留的检测.
건립료화장품중15충휘발성유궤용제잔류적정공기상색보측정방법.양품경60 ℃、30 min정태정공후,채용기상색보-경화염리자화검측기진행검측,외표법정량.가표회수시험결과표명:15충휘발성유궤용제잔류평균회수솔위62.8% ～116% ,상대표준편차균소우5% .방법적검출한위0.09～0.68 mg/kg.해방법가유효극복기체간우,일차진양가동시분리화측정화장품중15충휘발성유궤용제,준학령민,간단쾌속,괄용우화장품중휘발성유궤용제잔류적검측.
A headspace gas chromatography (HS-GC) method was developed for the rapid determination of multi-mixture of 15 residual volatile organic compounds in cosmetics. The experimental conditions of HS-GC such as headspace temperature, headspace time and the analytical conditions of GC were optimized. Cosmetic samples were extracted and cleaned-up by headspace at 60 ℃ for 30 min, determined by GC-flame ionization detector (FID) and quantified by external standard method. The 15 poisonous volatile organic compounds were separated efficiently from impurities with high sensitivity and reproducibility. The relative standard deviations (RSDs) were less than 5% , the recoveries were from 62.8% -116% , the linear range was 0.002-2.0 mg/L with a good linear correlation coefficient (r＞0.999) and the limits of detection were 0.09-0.68 mg/kg. By means of the above developed HS-GC method, 15 residual volatile organic compounds in cosmetics were detected accurately and simultaneously in a single sample injection. The method is accurate, simple, rapid, and is suitable for the trace analysis of multi-mixture of residual volatile organic compounds in various cosmetics.