中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
6期
8-10
,共3页
舒芬太尼%镇痛%氟比洛芬
舒芬太尼%鎮痛%氟比洛芬
서분태니%진통%불비락분
Sufentanil%Analgesia%Flurbiprofen
目的 探讨氟比洛芬酯联合舒芬太尼在腹腔镜胆囊切除术后镇痛的效果.方法 选择择期全身麻醉下行腹腔镜胆囊切除术患者350例,按随机数字表法分为对照组(165例)和研究组(185例).对照组手术结束即刻静脉连接患者自控镇痛(PCA)泵,给予舒芬太尼200 μg+0.9%氯化钠100 ml;研究组于手术结束前30 min给予氟比洛芬酯50 mg,手术结束即刻连接PCA泵给予舒芬太尼100μg+氟比洛芬酯50mg+0.9%氯化钠100ml.采用视觉模拟评分(VAS)评价两组术后1、4、8、12、24 h的疼痛程度,并观察有无恶心、呕吐、呼吸抑制、皮肤瘙痒等不良反应.结果 研究组术后各时间点VAS明显低于对照组(P＜0.05).对照组发生恶心61例、呕吐53例、皮肤瘙痒36例,研究组分别为25、25、15例,对照组各种不良反应发生例数明显多于研究组(P＜0.05).两组均未发生呼吸抑制.结论 腹腔镜胆囊切除术患者术后应用氟比洛芬酯联合舒芬太尼的镇痛效果好于单纯使用舒芬太尼,且可减少不良反应.
目的 探討氟比洛芬酯聯閤舒芬太尼在腹腔鏡膽囊切除術後鎮痛的效果.方法 選擇擇期全身痳醉下行腹腔鏡膽囊切除術患者350例,按隨機數字錶法分為對照組(165例)和研究組(185例).對照組手術結束即刻靜脈連接患者自控鎮痛(PCA)泵,給予舒芬太尼200 μg+0.9%氯化鈉100 ml;研究組于手術結束前30 min給予氟比洛芬酯50 mg,手術結束即刻連接PCA泵給予舒芬太尼100μg+氟比洛芬酯50mg+0.9%氯化鈉100ml.採用視覺模擬評分(VAS)評價兩組術後1、4、8、12、24 h的疼痛程度,併觀察有無噁心、嘔吐、呼吸抑製、皮膚瘙癢等不良反應.結果 研究組術後各時間點VAS明顯低于對照組(P＜0.05).對照組髮生噁心61例、嘔吐53例、皮膚瘙癢36例,研究組分彆為25、25、15例,對照組各種不良反應髮生例數明顯多于研究組(P＜0.05).兩組均未髮生呼吸抑製.結論 腹腔鏡膽囊切除術患者術後應用氟比洛芬酯聯閤舒芬太尼的鎮痛效果好于單純使用舒芬太尼,且可減少不良反應.
목적 탐토불비락분지연합서분태니재복강경담낭절제술후진통적효과.방법 선택택기전신마취하행복강경담낭절제술환자350례,안수궤수자표법분위대조조(165례)화연구조(185례).대조조수술결속즉각정맥련접환자자공진통(PCA)빙,급여서분태니200 μg+0.9%록화납100 ml;연구조우수술결속전30 min급여불비락분지50 mg,수술결속즉각련접PCA빙급여서분태니100μg+불비락분지50mg+0.9%록화납100ml.채용시각모의평분(VAS)평개량조술후1、4、8、12、24 h적동통정도,병관찰유무악심、구토、호흡억제、피부소양등불량반응.결과 연구조술후각시간점VAS명현저우대조조(P＜0.05).대조조발생악심61례、구토53례、피부소양36례,연구조분별위25、25、15례,대조조각충불량반응발생례수명현다우연구조(P＜0.05).량조균미발생호흡억제.결론 복강경담낭절제술환자술후응용불비락분지연합서분태니적진통효과호우단순사용서분태니,차가감소불량반응.
Objective To explore the analgesic effect of the combination of flurbiprofen axetil with sufentanil for patients after laparoscopic cholecystectomy. Methods Three hundred and fifty patients underwent laparoscopic surgery were divided into study group( 185 cases) and control group( 165 cases) by random digits table. The patients were treated by postoperative sufentanil 200 μ g in 0.9% sodium chloride 100 ml in control.group, while the patients in study group were treated by preoperative flurbiprofen axetil 50mg and postoperative sufentanil 100 μg + flurbiprofen axetil 50 mg in 0.9% sodium chloride 100 ml. The pain was evaluated at 1,4,8,12,24 h after operation by visual simulation score (VAS),the adverse effect example for nausea,vomit,respiratory depression,itch of skin were observed. Results The VAS were significantly higher in control group at various times than those in study group(P＜ 0.05 ). Sixty-one cases with nausea, 53 cases with vomit, 36 cases with itch of skin in control group, and 25,25,15 cases in study group,the incidence of adverse effect was significantly lower in study group than that in control group (P＜0.05).There was no respiratory depression occurring in two groups. Conclusion Flurbiprofen axetil combined with sufentanil has better analgesic effect and lower adverse effects than sufentanil alone.
