中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2011年
10期
969-972
,共4页
陈少科%罗静思%秦映芬%范歆%唐晴%冯莹
陳少科%囉靜思%秦映芬%範歆%唐晴%馮瑩
진소과%라정사%진영분%범흠%당청%풍형
肥胖%代谢综合征%危险因素
肥胖%代謝綜閤徵%危險因素
비반%대사종합정%위험인소
Obesity%Metabolic syndrome%Risk factor
目的 分析儿童青少年肥胖与代谢综合征(MS)相关性及危险因素.方法 采用分层整群随机抽样方法从南宁市396所中小学抽取14所学校6~18岁中小学生7893人,进行体格检查及空腹血糖(FBG)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、空腹胰岛素(FINS)的血液生化检测,并计算胰岛素抵抗指数(HOMA-IR).结果 (1)MS患病率为正常组0.57%、超重组4.53%、肥胖组26.80%.(2)除HDL-C均值随肥胖增加而降低外,其余各指标均值、异常率比较均为肥胖组>超重组>正常组,3组间差异有统计学意义(P<0.05).(3)对MS有影响的指标为腰围(OR=1.087,95%CI:1.033~1.143)、SBP(OR=1.073,95%CI:1.032 ~ 1.1 16)、FBG(OR=1.394,95%CI:1.568 ~3.423)、TG(OR=3.213,95%CI:1.410 ~ 7.319)、HDL-C(OR=0.001,95% CI:0.000~0.012).结论 儿童青少年MS与肥胖密切相关,其患病率和危险因素随着肥胖程度的加重而增加.
目的 分析兒童青少年肥胖與代謝綜閤徵(MS)相關性及危險因素.方法 採用分層整群隨機抽樣方法從南寧市396所中小學抽取14所學校6~18歲中小學生7893人,進行體格檢查及空腹血糖(FBG)、總膽固醇(TC)、甘油三酯(TG)、高密度脂蛋白膽固醇(HDL-C)、低密度脂蛋白膽固醇(LDL-C)、丙氨痠氨基轉移酶(ALT)、天門鼕氨痠氨基轉移酶(AST)、空腹胰島素(FINS)的血液生化檢測,併計算胰島素牴抗指數(HOMA-IR).結果 (1)MS患病率為正常組0.57%、超重組4.53%、肥胖組26.80%.(2)除HDL-C均值隨肥胖增加而降低外,其餘各指標均值、異常率比較均為肥胖組>超重組>正常組,3組間差異有統計學意義(P<0.05).(3)對MS有影響的指標為腰圍(OR=1.087,95%CI:1.033~1.143)、SBP(OR=1.073,95%CI:1.032 ~ 1.1 16)、FBG(OR=1.394,95%CI:1.568 ~3.423)、TG(OR=3.213,95%CI:1.410 ~ 7.319)、HDL-C(OR=0.001,95% CI:0.000~0.012).結論 兒童青少年MS與肥胖密切相關,其患病率和危險因素隨著肥胖程度的加重而增加.
목적 분석인동청소년비반여대사종합정(MS)상관성급위험인소.방법 채용분층정군수궤추양방법종남저시396소중소학추취14소학교6~18세중소학생7893인,진행체격검사급공복혈당(FBG)、총담고순(TC)、감유삼지(TG)、고밀도지단백담고순(HDL-C)、저밀도지단백담고순(LDL-C)、병안산안기전이매(ALT)、천문동안산안기전이매(AST)、공복이도소(FINS)적혈액생화검측,병계산이도소저항지수(HOMA-IR).결과 (1)MS환병솔위정상조0.57%、초중조4.53%、비반조26.80%.(2)제HDL-C균치수비반증가이강저외,기여각지표균치、이상솔비교균위비반조>초중조>정상조,3조간차이유통계학의의(P<0.05).(3)대MS유영향적지표위요위(OR=1.087,95%CI:1.033~1.143)、SBP(OR=1.073,95%CI:1.032 ~ 1.1 16)、FBG(OR=1.394,95%CI:1.568 ~3.423)、TG(OR=3.213,95%CI:1.410 ~ 7.319)、HDL-C(OR=0.001,95% CI:0.000~0.012).결론 인동청소년MS여비반밀절상관,기환병솔화위험인소수착비반정도적가중이증가.
Objective To investigate the association between obesity and prevalence of metabolic syndrome (MS) with its associated risk factors,in children and adolescents.Methods A stratified random sampling method was used to select 7893 students from 6 to 18 years of age from 14 out of 396 primary and secondary schools in Nanning city.All the students had undergone physical examination and blood tests including the following risk factors related to metabolic syndrome:fasting blood glucose (FBG),total cholesterol (TC),triglycerides (TG),high-density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),alanine amino shift enzyme (ALT),aspartic acid amine shift enzyme (AST) and fasting insulin (FINS).The homeostasis model assessment insulin resistance index (HOMA-IR) was also measured.Results (1) The prevalence rate of MS in normal group was 0.57%.In both the overweight and obesity groups,the prevalence rates of MS were 4.53% and 26.80%,respectively.(2) These indices in obesity group were higher than other two groups (P<0.05).The result of overweight group was higher than normal group (P<0.05).(3) Waist circumference(OR=1.087,95%CI:1.033-1.143 ),SBP ( OR=1.073,95%CI:1.032-1.116),FBG (OR=1.394,95%CI:1.568-3.423),TG (OR=3.213,95%CI:1.410-7.319) and HDL-C (OR=0.001,95%CI:0.000-0.012)were detecting indices which had statistically significant with MS in binary logistic regression analysis.Conclusion Metabolic syndrome and obesity were closely related in children and adolescents while its prevalence and risk factors increased with the severity of obesity.