CAJ | 학술논문

胰腺癌是一种常见的恶性消化道肿瘤,近年来其发病率有明显上升的趋势.由于早期症状不明显,临床确诊的胰腺癌患者多已处于中晚期,大多失去手术治疗机会,预后极差.因此,提高胰腺癌的早期诊断率非常重要.近年来,蛋白质组学发展迅速,广泛应用于临床研究,特别是胰腺癌肿瘤标志物的研究.本文就蛋白质组学技术在胰腺癌血清、胰液、胰腺癌组织细胞和胰腺癌细胞中的应用作一综述.
이선암시일충상견적악성소화도종류,근년래기발병솔유명현상승적추세.유우조기증상불명현,림상학진적이선암환자다이처우중만기,대다실거수술치료궤회,예후겁차.인차,제고이선암적조기진단솔비상중요.근년래,단백질조학발전신속,엄범응용우림상연구,특별시이선암종류표지물적연구.본문취단백질조학기술재이선암혈청、이액、이선암조직세포화이선암세포중적응용작일종술.
Pancreatic cancer is a commonly malignant gastrointestinal tumor with an significantly increasing incidence.Those patients without nonspecific symptoms at early stage had mostly lost the opportunity of surgical therapy when pancreatic cancer was detected at advanced stage,and its prognosis is poor.Therefore,it is rather important to improve the early diagnosis of pancreatic cancer.In recent years,proteomics is developing rapidly.Proteomics technologies have been widely used in clinical research.Using proteomics technology screening pancreatic cancer tumor markers becomes the research focus,thus we try to find a kind of or a group of pancreatic tumor markers,so as to improve the diagnosis of pancreatic cancer.