中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2011年
3期
227-230
,共4页
角膜移植%小地区分析%外科手术%数据收集
角膜移植%小地區分析%外科手術%數據收集
각막이식%소지구분석%외과수술%수거수집
Corneal transplantation%Small-area analysis%Surgical procedure,operative%Data collection
目的 分析1999年9月至2009年12月在浙江省温州医学院附属眼视光医院施行角膜移植手术病例的病因以及手术方式的变化趋势.方法 调查研究.统计1999年9月至2009年12月在眼视光医院施行角膜移植手术患者的病因,并记录患者的年龄、性别、籍贯、诊断、手术方式等相关信息,把上述信息输入Excel表格中,进行描述性分析,计算百分比,结果用各种统计图表来表示.结果 这10年间行角膜移植手术患者的年龄分布呈正态性,平均为44.4岁,高峰在50～59岁.男性患者多于女性患者,男性患者在细菌件角膜病变和外伤中所占的百分比明显高于女性.近2/3患者来源于温州地区.共对651例患者(727眼)施行了角膜移植手术,其中439例(495眼)行穿透性角膜移植术,103例(123眼)行深板层角膜移植术,62例(62眼)行板层角膜移植术,40例(40眼)行穿透性角膜移植联合白内障摘除手术,7例(7眼)行其他类型角膜移植手术.最常见的病因为感染性角膜病变,168眼(23.1%),其中细菌性角膜溃疡86眼(11.8%),真菌性角膜溃疡82眼(11.3%).其他的有单纯疱疹病毒性角膜炎165眼(22.7%),角膜白斑(包括先天性白斑以及感染愈合后遗留的白斑)95眼(13.1%),外伤(包括化学伤、热烧伤、爆炸伤以及外伤后角膜疤痕)64眼(8.8%),圆锥角膜58眼(8.0%),大泡性角膜病变(人工晶状体眼或无晶状体眼)57眼(7.8%),角结膜皮样瘤(包括Goldenharr综合征)43眼(5.9%)以及各种类型角膜营养不良和变性41眼(5.6%),24眼(3.3%)为再次移植.穿透性角膜移植手术量从2005年后有逐渐下降趋势,而板层和深板层角膜移植手术量有逐渐增加趋势.结论 感染性角膜病变是温州地区角膜移植最常见的病因,单纯疱疹病毒性角膜炎是单病种中最多见的病因.本次研究结果和中国北部地区结果相似,和欧美国家结果有所不同.对于内皮功能正常的患者,深板层角膜移植术将逐渐取代穿透性角膜移植术.
目的 分析1999年9月至2009年12月在浙江省溫州醫學院附屬眼視光醫院施行角膜移植手術病例的病因以及手術方式的變化趨勢.方法 調查研究.統計1999年9月至2009年12月在眼視光醫院施行角膜移植手術患者的病因,併記錄患者的年齡、性彆、籍貫、診斷、手術方式等相關信息,把上述信息輸入Excel錶格中,進行描述性分析,計算百分比,結果用各種統計圖錶來錶示.結果 這10年間行角膜移植手術患者的年齡分佈呈正態性,平均為44.4歲,高峰在50～59歲.男性患者多于女性患者,男性患者在細菌件角膜病變和外傷中所佔的百分比明顯高于女性.近2/3患者來源于溫州地區.共對651例患者(727眼)施行瞭角膜移植手術,其中439例(495眼)行穿透性角膜移植術,103例(123眼)行深闆層角膜移植術,62例(62眼)行闆層角膜移植術,40例(40眼)行穿透性角膜移植聯閤白內障摘除手術,7例(7眼)行其他類型角膜移植手術.最常見的病因為感染性角膜病變,168眼(23.1%),其中細菌性角膜潰瘍86眼(11.8%),真菌性角膜潰瘍82眼(11.3%).其他的有單純皰疹病毒性角膜炎165眼(22.7%),角膜白斑(包括先天性白斑以及感染愈閤後遺留的白斑)95眼(13.1%),外傷(包括化學傷、熱燒傷、爆炸傷以及外傷後角膜疤痕)64眼(8.8%),圓錐角膜58眼(8.0%),大泡性角膜病變(人工晶狀體眼或無晶狀體眼)57眼(7.8%),角結膜皮樣瘤(包括Goldenharr綜閤徵)43眼(5.9%)以及各種類型角膜營養不良和變性41眼(5.6%),24眼(3.3%)為再次移植.穿透性角膜移植手術量從2005年後有逐漸下降趨勢,而闆層和深闆層角膜移植手術量有逐漸增加趨勢.結論 感染性角膜病變是溫州地區角膜移植最常見的病因,單純皰疹病毒性角膜炎是單病種中最多見的病因.本次研究結果和中國北部地區結果相似,和歐美國傢結果有所不同.對于內皮功能正常的患者,深闆層角膜移植術將逐漸取代穿透性角膜移植術.
목적 분석1999년9월지2009년12월재절강성온주의학원부속안시광의원시행각막이식수술병례적병인이급수술방식적변화추세.방법 조사연구.통계1999년9월지2009년12월재안시광의원시행각막이식수술환자적병인,병기록환자적년령、성별、적관、진단、수술방식등상관신식,파상술신식수입Excel표격중,진행묘술성분석,계산백분비,결과용각충통계도표래표시.결과 저10년간행각막이식수술환자적년령분포정정태성,평균위44.4세,고봉재50～59세.남성환자다우녀성환자,남성환자재세균건각막병변화외상중소점적백분비명현고우녀성.근2/3환자래원우온주지구.공대651례환자(727안)시행료각막이식수술,기중439례(495안)행천투성각막이식술,103례(123안)행심판층각막이식술,62례(62안)행판층각막이식술,40례(40안)행천투성각막이식연합백내장적제수술,7례(7안)행기타류형각막이식수술.최상견적병인위감염성각막병변,168안(23.1%),기중세균성각막궤양86안(11.8%),진균성각막궤양82안(11.3%).기타적유단순포진병독성각막염165안(22.7%),각막백반(포괄선천성백반이급감염유합후유류적백반)95안(13.1%),외상(포괄화학상、열소상、폭작상이급외상후각막파흔)64안(8.8%),원추각막58안(8.0%),대포성각막병변(인공정상체안혹무정상체안)57안(7.8%),각결막피양류(포괄Goldenharr종합정)43안(5.9%)이급각충류형각막영양불량화변성41안(5.6%),24안(3.3%)위재차이식.천투성각막이식수술량종2005년후유축점하강추세,이판층화심판층각막이식수술량유축점증가추세.결론 감염성각막병변시온주지구각막이식최상견적병인,단순포진병독성각막염시단병충중최다견적병인.본차연구결과화중국북부지구결과상사,화구미국가결과유소불동.대우내피공능정상적환자,심판층각막이식술장축점취대천투성각막이식술.
Objective To analyze the indications for keratoplasty at Eye Hospital of Wenzhou Medical College, Zhejiang province, from September 1999 to December 2009 and the trend of surgical procedures. Methods The investigation involved an analysis of the indications for these patients, and age, gender, place of residence, diagnosis, surgical procedure, etc., were recorded. All the information was input into an Excel format for descriptive analysis. Results were illustrated with graphs and format. Results During the approximate ten-year span, patient age distribution was bimodal, the average age was 44.4 years with peaks in the 6th decade. There were more male than female patients. There was a higher percentage of male patients with bacterial keratitis and trauma than for women. Nearly two-thirds of the patients were from the Wenzhou area. There were 651 cases (727 eyes) underwent corneal surgery in our study. This included 439 cases (495 eyes) of penetrating keratoplasty, 103 cases (123 eyes) of deep lamellar keratoplasty, 62 cases (62 eyes) of lamellar keratoplasty, 40 cases (40 eyes) of keratoplasty combined with cataract surgery and 7 cases (7 eyes) with other types of keratoplasty. The leading indications for keratoplasty were infectious keratitis (168, 23.1%), including bacterial keratitis (86, 11.8%) and fungal keratitis (82, 11.3%). This was followed by herpes simplex keratitis (165, 22.7%) and corneal scarring (95, 13.1%), including congenital corneal scarring and scarring from infection, trauma (64, 8.8%), including chemical burn, thermal burn and explosion injury, keratoconus (58, 8.0%), bullous keratopathy (pseudophakic or aphakic) (57, 7.8%), corneal dermoid (including Goldenharr syndrome) (43, 5.9%), corneal dystrophy and degeneration (41, 5.6%) and regrafting (24, 3.3%). The number of penetrating keratoplasty cases has gradually declined since 2005 and lamellar and deep lamellar keratoplasty cases have shown a gradually increasing trend. Conclusion In our study, infectious keratitis was the leading indicator for keratoplasty at Wenzhou area. Herpes simplex keratitis was the leading indicator for a single disease. This was similar to northern China, but different from European and American countries. For patients with normal endothelial function, deep lamellar keratoplasty will gradually replace penetrating keratoplasty as the leading surgery.
