CAJ | 학술논문

目的探讨腹泻患儿轮状病毒感染与心肌、肝脏损害的关系.方法对321例住院腹泻患儿用胶体金法检测粪便轮状病毒抗原并做心肌酶及肝功检测.结果观察组(粪便轮状病毒抗原检测阳性)与对照组(粪便轮状病毒抗原检测阴性)心肌损害及肝损害的发生率比较,观察组明显高于对照组,差异有显著性(P值<0.05);全部病例中,小年龄组较大年龄组心肌损害及肝功损害发生率高,同年龄段中观察组的肝损害和心肌损害发生率明显高于对照组.对比差异有显著性(P值<0.05);全部病例中,随着脱水程度的增加,心肌酶和肝功能异常率有增高趋势,相同脱水程度情况下观察组的肝损害和心肌损害发生率明显高于对照组,两组对比差异有显著性(P值<0.05);全部病例中心肌酶及肝功能指标治疗前、后的对比有显著性差异(P值<0.05).结论轮状病毒感染常合并心肌损害及肝损害,且年龄小者受损害的机率较大,随着脱水程度的增加,心肌酶和肝功能异常率有增高趋势.临床医生对腹泻患儿应注意粪便轮状病毒抗原及心肌酶、肝功的检测,并给予及时有针对性的治疗.
목적 탐토복사환인륜상병독감염여심기、간장손해적관계.방법 대321례주원복사환인용효체금법검측분편륜상병독항원병주심기매급간공검측.결과 관찰조(분편륜상병독항원검측양성)여대조조(분편륜상병독항원검측음성)심기손해급간손해적발생솔비교,관찰조명현고우대조조,차이유현저성(P치<0.05);전부병례중,소년령조교대년령조심기손해급간공손해발생솔고,동년령단중관찰조적간손해화심기손해발생솔명현고우대조조.대비차이유현저성(P치<0.05);전부병례중,수착탈수정도적증가,심기매화간공능이상솔유증고추세,상동탈수정도정황하관찰조적간손해화심기손해발생솔명현고우대조조,량조대비차이유현저성(P치<0.05);전부병례중심기매급간공능지표치료전、후적대비유현저성차이(P치<0.05).결론 륜상병독감염상합병심기손해급간손해,차년령소자수손해적궤솔교대,수착탈수정도적증가,심기매화간공능이상솔유증고추세.림상의생대복사환인응주의분편륜상병독항원급심기매、간공적검측,병급여급시유침대성적치료.
Objective To investigate the diarrhea rotavirus infection and cardiac muscle, liver damage relations.Methods 321 oases of hospitalized children with diarrhea were detected using colloidal gold and do stool rotavirus antigen detection of myocardial enzymes and liver function.Results The obser- vation group ( stool rotavirus antigen test positive ) and the control group ( stool rotavirus antigen test negative ) myoeardial injury incidence of liver damage compared to the observation group was significantly higher, the difference was significant ( P<0.05 ); Among all group, there are a higher incidence of myoeardial injury and liver damage in the small age group than in the older age group, there is a significant difference ( P<. 0.05 ).Among all groups, enzymes and liver function abnormal rate increased tendency with the degree of dehydration increases, there was a significant difference ( P< 0.05); Myocardial enzymes and liver function parameters before and after treatment in contrast to a significant difference( P<0. 05 ).Conclusions Rotavirus infection is often associated with myoeardial damage and liver damage, and the younger, more likely to be penalized, with the degree of dehydration increased, abnormal liver function enzymes, and the trend rate of increase.Clinicians should pay attention to the diarrhea stool rotavirus antigen and cardiac enzymes, liver function testing, and provide timely and targeted treatment.