中华创伤骨科杂志
中華創傷骨科雜誌
중화창상골과잡지
CHINESE JOURNAL OF ORTHOPAEDIC TRAUMA
2011年
8期
758-761
,共4页
骨折固定术,内%骨折愈合%镍钛合金
骨摺固定術,內%骨摺愈閤%鎳鈦閤金
골절고정술,내%골절유합%얼태합금
Fracture fixation,internal%Fracture healing%NiTi shape memory alloy
目的 观察持续应力下松质骨骨折愈合的细胞超微结构变化,探讨持续应力对松质骨骨折愈合的影响.方法 取20只家犬两侧股骨转子部"L"型截骨,左侧以镍钛合金粗隆截骨固定器固定,右侧以钢丝贯穿环扎加压收紧固定.术后2、4、8、12周取材行透射电镜观察.结果 镍钛合金粗隆截骨固定器组内固定后骨折愈合时间早于钢丝固定组,且2种不同固定方式下骨折断端间成骨细胞、成软骨细胞及胶原纤维表型及形态均有明显不同,镍钛合金粗隆截骨固定器组细胞及胶原纤维排列表现出明显的同向性,与应力作用方向一致.细胞的增生及胶原的合成也较钢丝组旺盛.结论 在镍钛合金转子截骨固定器固定形成的骨折断端间持续应力作用下,松质骨骨折能够获得快速、有效地修复及愈合.
目的 觀察持續應力下鬆質骨骨摺愈閤的細胞超微結構變化,探討持續應力對鬆質骨骨摺愈閤的影響.方法 取20隻傢犬兩側股骨轉子部"L"型截骨,左側以鎳鈦閤金粗隆截骨固定器固定,右側以鋼絲貫穿環扎加壓收緊固定.術後2、4、8、12週取材行透射電鏡觀察.結果 鎳鈦閤金粗隆截骨固定器組內固定後骨摺愈閤時間早于鋼絲固定組,且2種不同固定方式下骨摺斷耑間成骨細胞、成軟骨細胞及膠原纖維錶型及形態均有明顯不同,鎳鈦閤金粗隆截骨固定器組細胞及膠原纖維排列錶現齣明顯的同嚮性,與應力作用方嚮一緻.細胞的增生及膠原的閤成也較鋼絲組旺盛.結論 在鎳鈦閤金轉子截骨固定器固定形成的骨摺斷耑間持續應力作用下,鬆質骨骨摺能夠穫得快速、有效地脩複及愈閤.
목적 관찰지속응력하송질골골절유합적세포초미결구변화,탐토지속응력대송질골골절유합적영향.방법 취20지가견량측고골전자부"L"형절골,좌측이얼태합금조륭절골고정기고정,우측이강사관천배찰가압수긴고정.술후2、4、8、12주취재행투사전경관찰.결과 얼태합금조륭절골고정기조내고정후골절유합시간조우강사고정조,차2충불동고정방식하골절단단간성골세포、성연골세포급효원섬유표형급형태균유명현불동,얼태합금조륭절골고정기조세포급효원섬유배렬표현출명현적동향성,여응력작용방향일치.세포적증생급효원적합성야교강사조왕성.결론 재얼태합금전자절골고정기고정형성적골절단단간지속응력작용하,송질골골절능구획득쾌속、유효지수복급유합.
Objective To explore the effect of persistent stress on the ultrastructure of cancellous bone in the process of fracture healing.Method A transverse osteotomy on both sides of the femoral tuberositas was performed in 20 adult dogs. One side was fixed with a self-designed tuberositas memofy-pressure connector (TMC) which was made of NiTi shape memory alloy, and the other with compressive steel-wire (SW) cerclage.Five animals in each group were sacrificed at 2, 4, 8, 12 weeks after operation and observed under transmission electron microscope.Results The fracture healing was accelerated in the TMC group.The osteoblasts, chondroblasts and collagen fibers at the fracture sites showed significantly different morphology between the 2 groups at every observation time.Most cells and collagen fibers in the TMC group grew along the same direction as the stress, but those in the SW group grew in disorder.Both the number and functional activity of the osteoblasts and chondroblasts were higher in the TMC group than in the SW group.Conclusion Persistent stress can enhance healing and bone reconstruction following a cancellous bone fracture.
