中华神经外科杂志
中華神經外科雜誌
중화신경외과잡지
Chinese Journal of Neurosurgery
2010年
2期
138-141
,共4页
唐晓平%张涛%彭华%余定庸%唐文国%漆建%罗仁国%冯凌%王远传%苟章洋%陈灵%梅才君
唐曉平%張濤%彭華%餘定庸%唐文國%漆建%囉仁國%馮凌%王遠傳%茍章洋%陳靈%梅纔君
당효평%장도%팽화%여정용%당문국%칠건%라인국%풍릉%왕원전%구장양%진령%매재군
脑膜瘤%脑水肿%高压氧,治疗
腦膜瘤%腦水腫%高壓氧,治療
뇌막류%뇌수종%고압양,치료
Meningioma%Brain edema%Hyperbaric oxygenation,therapy
目的 探讨高压氧(HBO)在瘤周水肿明显的脑膜瘤术后的治疗作用.方法 将232例瘤周水肿明显的脑膜瘤根据术前、术后平衡的原则分为HBO治疗组和对照组,各116例.HBO治疗组在对照组治疗的基础上,早期应用高压氧治疗,术后半个月统计两组患者的机能状态(KPS评分)、术区水肿体积,术后半年统计两组患者术区异常密度影体积和神经功能障碍例数,并做统计学分析.结果 两组患者术后3 d KPS评分及术区水肿体积差异无统计学意义(P>0.05);术后半个月HBO治疗组KPS评分高于对照组,术区水肿体积明显小于对照组,两组比较差异有统计学意义(P<0.05);术后半年HBO治疗组术区异常密度体积小于对照组(P<0.05),HBO治疗组出现过癫痫、失语或轻瘫等神经功能障碍的例数少于对照组(P<0.01).结论 术后早期应用高压氧治疗瘤周水肿明显的脑膜瘤,可减轻水肿体积,提高KPS评分和降低神经功能障碍的发生率,有较好的临床应用价值.
目的 探討高壓氧(HBO)在瘤週水腫明顯的腦膜瘤術後的治療作用.方法 將232例瘤週水腫明顯的腦膜瘤根據術前、術後平衡的原則分為HBO治療組和對照組,各116例.HBO治療組在對照組治療的基礎上,早期應用高壓氧治療,術後半箇月統計兩組患者的機能狀態(KPS評分)、術區水腫體積,術後半年統計兩組患者術區異常密度影體積和神經功能障礙例數,併做統計學分析.結果 兩組患者術後3 d KPS評分及術區水腫體積差異無統計學意義(P>0.05);術後半箇月HBO治療組KPS評分高于對照組,術區水腫體積明顯小于對照組,兩組比較差異有統計學意義(P<0.05);術後半年HBO治療組術區異常密度體積小于對照組(P<0.05),HBO治療組齣現過癲癇、失語或輕癱等神經功能障礙的例數少于對照組(P<0.01).結論 術後早期應用高壓氧治療瘤週水腫明顯的腦膜瘤,可減輕水腫體積,提高KPS評分和降低神經功能障礙的髮生率,有較好的臨床應用價值.
목적 탐토고압양(HBO)재류주수종명현적뇌막류술후적치료작용.방법 장232례류주수종명현적뇌막류근거술전、술후평형적원칙분위HBO치료조화대조조,각116례.HBO치료조재대조조치료적기출상,조기응용고압양치료,술후반개월통계량조환자적궤능상태(KPS평분)、술구수종체적,술후반년통계량조환자술구이상밀도영체적화신경공능장애례수,병주통계학분석.결과 량조환자술후3 d KPS평분급술구수종체적차이무통계학의의(P>0.05);술후반개월HBO치료조KPS평분고우대조조,술구수종체적명현소우대조조,량조비교차이유통계학의의(P<0.05);술후반년HBO치료조술구이상밀도체적소우대조조(P<0.05),HBO치료조출현과전간、실어혹경탄등신경공능장애적례수소우대조조(P<0.01).결론 술후조기응용고압양치료류주수종명현적뇌막류,가감경수종체적,제고KPS평분화강저신경공능장애적발생솔,유교호적림상응용개치.
Objective To explore the effect of hyperbaric oxygen(HBO) on treating meningeoma with peritumoral brain edema after tumorectomy. Methods According to the principle of holding the balance of preoperative and postoperative, the clinical data of 232 patients with peripheral edema around meningeoma were divided into experimental group and control group, that each were 116 cases. HBO therapy was early applied in experimental group and other therapy was conformed to control group. The function state (KPS score), operative regional edema volume of these groups were performed inductive statistics at half months after tumoreetomy. The cases of abnormal operative regional density image and neurofunctional disturbance at half years after operation were analyzed. Result The KPS score and operative regional edema volume have no significant difference between these two groups 3 days after operation (P>0. 05); the KPS score of experimental group was higher than control group at half months, and its edema volume was smaller(P<0.05) ; the operative regional edema volume of experimental group was smaller than control at half years (P<0.05), and the examples of experimental group who had generated epilepsy, aphasia, incomplete paralysis were smaller than control group ( P <0.01). Conclusion The meningeoma with significal peripheral edema should be applicated early HBO therapy after tumorectomy, and that often obtain better therapeutic efficacy.
