CAJ | 학술논문

目的探讨颞叶低级别胶质瘤继发顽固性癫痫患者的临床特点、术前评估及外科治疗效果.方法对31例颞叶低级别胶质瘤继发顽固性癫痫患者术前进行MRI、视频脑电图(VEEG)、发作间期正电子发射断层扫描(PET)检查,综合分析检查结果,制定相应手术方案.术中行皮层脑电描记(ECoG),术后对切除组织进行病理检查,并对患者进行术后随访.结果 29例(93.5%)患者术后癫痫发作完全或部分缓解,2例(6.5%)患者无明显缓解.结论对于颞叶低级别胶质瘤继发顽固性癲痫的患者,术前进行综合评估,同时切除病灶及致痫灶是控制癫痫发作、改善预后的有效手段.
목적 탐토섭협저급별효질류계발완고성전간환자적림상특점、술전평고급외과치료효과.방법 대31례섭협저급별효질류계발완고성전간환자술전진행MRI、시빈뇌전도(VEEG)、발작간기정전자발사단층소묘(PET)검사,종합분석검사결과,제정상응수술방안.술중행피층뇌전묘기(ECoG),술후대절제조직진행병리검사,병대환자진행술후수방.결과 29례(93.5%)환자술후전간발작완전혹부분완해,2례(6.5%)환자무명현완해.결론 대우섭협저급별효질류계발완고성전간적환자,술전진행종합평고,동시절제병조급치간조시공제전간발작、개선예후적유효수단.
Objective To investigate the clinical features and surgical treatment of intractable epilepsy to temporal low-grade gliomas.Methods MRI,Video electroencephaolgram (EEC),position emission tomography(PET) were performed in 31 patients with intractable epilepsy secondary to temporal low-grade gliomas before the surgery.The operative plans were made according to the outcomes of the above-mentioned examinations. The gliomas and epileptogenic foci were resected by neurosurgery assisted by intraoperative electrocorticogram in all the patients,who were followed up for 3 months after the surgery.Results Of 31 patients,29 (93.5%)were completely or partly free of seizure and 2 (6.5%)were insignificantly improved in seizure after the surgery.Conclusions The detailed operative plans before the surgery according the outcome of MRI,Video EEG and PET examinations are mecessary to the sucdcessful resetion of the gliomas and epileptogenic foci,which is important to improvement of the prognoses in the patients with intractable secondary to temporal low-grade gliomas.