CAJ | 학술논문

喹诺酮类药物是近20年来迅速发展起来的一类十分重要的广谱抗生素,能抑制细菌DNA螺旋酶,抗菌广谱高效低毒组织穿透力强,已成为兽医临诊和水产养殖中重要抗感染药物之一,被大量用于治疗、预防和促生长,由于其耐药性和潜在的致癌性引起广泛关注。本实验采用新一代的ELISA试剂盒检测喹诺酮类药物,与高效液相色谱法相比具有快速、简便、准确和灵敏度高等特点,能最大限度地减少操作误差和工作强度。
규낙동류약물시근20년래신속발전기래적일류십분중요적엄보항생소,능억제세균DNA라선매,항균엄보고효저독조직천투력강,이성위수의림진화수산양식중중요항감염약물지일,피대량용우치료、예방화촉생장,유우기내약성화잠재적치암성인기엄범관주。본실험채용신일대적ELISA시제합검측규낙동류약물,여고효액상색보법상비구유쾌속、간편、준학화령민도고등특점,능최대한도지감소조작오차화공작강도。
The quinolones are a kind of very important broad-spectrum antibiotics and developing rapidly in the recent twenty years, which can inhibit bacterial DNA helicase. They are characterized by wide antibacterial adaptability, low toxicity, strong organization wear deeply dint.They have become one of important anti-infective agents in veterinary clinical and aquaculture,which are widely used for treatment, prevention and promoting growth, aroused widespread concern because of their resistance and potential carcinogenicity.This study used a new generation of ELISA reagent box method to detect quinolones, the new method has such characteristics as quick, convenience, accuracy and high sensitivity, compared with a high performance liquid chromatography method. It can maximum limit reduce the operation errors and work intensity.