CAJ | 학술논문

目的应用组织多普勒技术评价代谢综合征(metabolic syndrome,MS)患者左心室的同步性.方法研究对象为22例MS伴左室肥厚患者(MS-LVH组)、69例MS不伴左室肥厚患者(MS-NLVH组)和33例正常人(对照组).测量左心室6个壁12个节段心肌收缩速度和舒张速度达峰时间(Ts,Te),应用12个节段Ts、Te最大值与最小值之差(Ts-diff,Te-diff)及标准差(Ts-SD,Te-SD)来评价左室收缩和舒张同步性.结果与对照组相比,MS-NLVH组和MS-LVH组Ts-diff、Ts-SD、Te-diff、Te-SD均显著增大,与MS-NLVH组相比,MS-LVH组Te-diff和Te-SD增大更加明显.结论 MS患者存在左室收缩和舒张同步性的异常,左室肥厚对舒张同步性的影响更加显著.
목적 응용조직다보륵기술평개대사종합정(metabolic syndrome,MS)환자좌심실적동보성.방법 연구대상위22례MS반좌실비후환자(MS-LVH조)、69례MS불반좌실비후환자(MS-NLVH조)화33례정상인(대조조).측량좌심실6개벽12개절단심기수축속도화서장속도체봉시간(Ts,Te),응용12개절단Ts、Te최대치여최소치지차(Ts-diff,Te-diff)급표준차(Ts-SD,Te-SD)래평개좌실수축화서장동보성.결과 여대조조상비,MS-NLVH조화MS-LVH조Ts-diff、Ts-SD、Te-diff、Te-SD균현저증대,여MS-NLVH조상비,MS-LVH조Te-diff화Te-SD증대경가명현.결론 MS환자존재좌실수축화서장동보성적이상,좌실비후대서장동보성적영향경가현저.
Objective To assess left ventricular synchronicity in patients with metabolic syndrome(MS)by tissue Doppler imaging.Methods Twenty-two patients with MS and left ventricular hypertrophy(LVH)(MS-LVH group),69 patients with MS and non-LVH(MS-NLVH group)and 33 healthy subjects(control group) were included.Left ventricular(LV)systolic and diastolic synchronicity were determined by measuring the maximal difference in time to peak myocardial systolic contraction(Ts-diff)and time to peak myocardial early diastolic relaxation(Te-diff),and the standard deviation of time to peak myocardial systolic contraction(Ts-SD)and early diastolic relaxation(Te-SD)with 6 basal and 6 middle LV segments.Results Compared with control group,patients with MS in MS-NLVH and MS-LVH group showed significantly prolonged Ts-diff,Ts-SD,Te-diff and Te-SD.Furthermore,Te-diff and Te-SD were much more prolonged in MS-LVH group than in MS-NLVH group.Conclusions Patients with MS have impaired L V systolic and diastolic synchronicity.LVH impacts the LV diastolic synchronicity much more obviously than systolic synchronicity in the patients with MS and LVH.