劳动医学
勞動醫學
노동의학
JOURNAL OF LABOUR MEDICINE
2001年
1期
22-25
,共4页
涂料%急性吸入毒性%呼吸道刺激性%TVOC含量%病理形态
塗料%急性吸入毒性%呼吸道刺激性%TVOC含量%病理形態
도료%급성흡입독성%호흡도자격성%TVOC함량%병리형태
[目的] 建立涂料急性吸入毒性检测方法和评价标准,探讨影响室内装潢涂料毒性的有关因素,为室内装潢涂料安全卫生质量的管理提供技术依据。 [方法] 通过44种室内装潢涂料急性吸入毒性和总挥发性有机物(TVOC)含量的测试,验证上述测试及评价方法的科学性和可行性。 [结果] 检测了6大类44种涂料,其中乳胶漆等水性涂料急性吸入毒性和呼吸道刺激性均为0级;溶剂型涂料急性吸入毒性大多在Ⅱ至Ⅲ级,个别达到Ⅳ级,并引起实验动物呼吸道和肺组织Ⅰ~Ⅱ级损伤。涂料的急性吸入毒性和呼吸道刺激性与TVOC含量具有明显的相关。 [结论] 室内装潢涂料的毒性:溶剂型涂料大于水性涂料,且毒性大小与涂料中的TVOC含量有关。涂料的急性吸入毒性强度分级和它们引起的病理形态学改变能有效地判断不同种类涂料的毒性大小。
[目的] 建立塗料急性吸入毒性檢測方法和評價標準,探討影響室內裝潢塗料毒性的有關因素,為室內裝潢塗料安全衛生質量的管理提供技術依據。 [方法] 通過44種室內裝潢塗料急性吸入毒性和總揮髮性有機物(TVOC)含量的測試,驗證上述測試及評價方法的科學性和可行性。 [結果] 檢測瞭6大類44種塗料,其中乳膠漆等水性塗料急性吸入毒性和呼吸道刺激性均為0級;溶劑型塗料急性吸入毒性大多在Ⅱ至Ⅲ級,箇彆達到Ⅳ級,併引起實驗動物呼吸道和肺組織Ⅰ~Ⅱ級損傷。塗料的急性吸入毒性和呼吸道刺激性與TVOC含量具有明顯的相關。 [結論] 室內裝潢塗料的毒性:溶劑型塗料大于水性塗料,且毒性大小與塗料中的TVOC含量有關。塗料的急性吸入毒性彊度分級和它們引起的病理形態學改變能有效地判斷不同種類塗料的毒性大小。
[목적] 건립도료급성흡입독성검측방법화평개표준,탐토영향실내장황도료독성적유관인소,위실내장황도료안전위생질량적관리제공기술의거。 [방법] 통과44충실내장황도료급성흡입독성화총휘발성유궤물(TVOC)함량적측시,험증상술측시급평개방법적과학성화가행성。 [결과] 검측료6대류44충도료,기중유효칠등수성도료급성흡입독성화호흡도자격성균위0급;용제형도료급성흡입독성대다재Ⅱ지Ⅲ급,개별체도Ⅳ급,병인기실험동물호흡도화폐조직Ⅰ~Ⅱ급손상。도료적급성흡입독성화호흡도자격성여TVOC함량구유명현적상관。 [결론] 실내장황도료적독성:용제형도료대우수성도료,차독성대소여도료중적TVOC함량유관。도료적급성흡입독성강도분급화타문인기적병리형태학개변능유효지판단불동충류도료적독성대소。
[Objective] This study was to establish a method for assessment of acute inhalation toxicity of coating,to explore the related factors affecting the toxicity of indoor coating,and to provide the technical basis for the safety and hygiene quality management of indoor coating. [Methods] The acute inhalation toxicity and total Volatile Organic Compounds (TVOC) were identified for 44 species in 6 categories of indoor coating,verifying the method of the measurement and assessment. [Results] The 44 species of indoor coating were classified according to both the acute inhalation toxicity and respiratory tract irritation,the aqueous coating such as emulsion paint etc belongs to class 0,the most of organic solvent coating to class Ⅱ or Ⅲ,and a few to Ⅳ. The certain kinds of coating can cause the damage of respiratory tract and lung tissue in degree from Ⅰ to Ⅱ in animal. The significant positive association was seen among the acute inhalation toxicity,respiratory tract irritation and the TVOC value of the coating. [Conclusion] Toxicity of the organic solvent coating is higher than that of the aqueous coating,and was related to the TVOC values. The toxicity of different kinds of coating can be efficiently identified by the acute inhalation toxicity classification and pathological findings described in this paper.