中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2010年
5期
307-308,313
,共3页
组织游离氨基酸%癌肿组织%癌旁乳腺组织
組織遊離氨基痠%癌腫組織%癌徬乳腺組織
조직유리안기산%암종조직%암방유선조직
Tissue free amino acids%Cancer tissue%Mammary gland tissue
目的 对乳腺癌癌肿组织、癌旁乳腺组织游离氨基酸的含量测定,比较两者游离氨基酸含量,探讨乳腺癌不平衡氨基酸治疗依据.方法 收集标本并保存,通过剪碎、研磨、匀浆、去蛋白质、分离出游离氨基酸、离心,检测癌肿组织与相应癌旁乳腺组织17种游离氨基酸的含量.结果 乳腺癌癌肿组织大部分游离氨基酸浓度高于癌旁乳腺组织游离氨基酸浓度.结论 乳腺癌癌肿组织氨基酸代谢与相应的癌旁乳腺组织氨基酸代谢存在明显的差异性,为乳腺癌不平衡氨基酸治疗提供参考依据.
目的 對乳腺癌癌腫組織、癌徬乳腺組織遊離氨基痠的含量測定,比較兩者遊離氨基痠含量,探討乳腺癌不平衡氨基痠治療依據.方法 收集標本併保存,通過剪碎、研磨、勻漿、去蛋白質、分離齣遊離氨基痠、離心,檢測癌腫組織與相應癌徬乳腺組織17種遊離氨基痠的含量.結果 乳腺癌癌腫組織大部分遊離氨基痠濃度高于癌徬乳腺組織遊離氨基痠濃度.結論 乳腺癌癌腫組織氨基痠代謝與相應的癌徬乳腺組織氨基痠代謝存在明顯的差異性,為乳腺癌不平衡氨基痠治療提供參攷依據.
목적 대유선암암종조직、암방유선조직유리안기산적함량측정,비교량자유리안기산함량,탐토유선암불평형안기산치료의거.방법 수집표본병보존,통과전쇄、연마、균장、거단백질、분리출유리안기산、리심,검측암종조직여상응암방유선조직17충유리안기산적함량.결과 유선암암종조직대부분유리안기산농도고우암방유선조직유리안기산농도.결론 유선암암종조직안기산대사여상응적암방유선조직안기산대사존재명현적차이성,위유선암불평형안기산치료제공삼고의거.
Objective To assay free amino acids (FAA) content of breast cancer tissue and mammary glandular tissue and discuss the therapeutic basis of unbalanced amino acids of breast cancer. Methods The selected samples were conserved and then cut into pieces, grinded, syruped and deproteinized. Then FAA were separated from the samples. The content of 17 kinds of free amino acids in breast cancer tissue and mammary glandular were assayed respectively. Results The concentration of FAA in breast cancer tissue was higher than that in mammary glandular tissue. Conclusions Free amino acids metabolism was greatly different in breast cancer and mammary glandular tissues. This offers a therapeutic basis for the treatment of unbalanced free amino acids in the case of breast cancer.
