CAJ | 학술논문

目的探讨测定血浆脑钠素水平对鉴别肺源性心脏病和高血压性心脏病所致心力衰竭的意义.方法肺源性心脏病、高血压性心脏病患者各30例,测定平均心率和PaO2,通过快速免疫荧光定量分析法测定血浆脑钠素水平,与30名正常健康人进行比较和分析.结果肺源性心脏病和高血压性心脏病两组患者在心力衰竭时血浆脑钠素水平均高于对照组(P＜0.05),其中高血压性心脏病组脑钠素[(597±68)ng/L]明显高于肺源性心脏病组[(179±34)ng/ml,P＜0.01].结论肺源性心脏病和高血压性心脏病患者心力衰竭时均表现出呼吸困难,血浆脑钠素可以作为鉴别两者的指标之一.
목적 탐토측정혈장뇌납소수평대감별폐원성심장병화고혈압성심장병소치심력쇠갈적의의.방법 폐원성심장병、고혈압성심장병환자각30례,측정평균심솔화PaO2,통과쾌속면역형광정량분석법측정혈장뇌납소수평,여30명정상건강인진행비교화분석.결과 폐원성심장병화고혈압성심장병량조환자재심력쇠갈시혈장뇌납소수평균고우대조조(P＜0.05),기중고혈압성심장병조뇌납소[(597±68)ng/L]명현고우폐원성심장병조[(179±34)ng/ml,P＜0.01].결론 폐원성심장병화고혈압성심장병환자심력쇠갈시균표현출호흡곤난,혈장뇌납소가이작위감별량자적지표지일.
Objective To study the significance of plasma brain natriuretic peptide(BNP)in differentiating patients with chronic cor pulmonale from those with hypertensive heart failure.Methods Thirty cases of cor pulmonale and 30 of hypertensive heart disease were recruited for the study.Heart rate and arterial partial oxygen pressure(PaO2)were measured for them,as well as plasma level of BNP Was measured by rapid immunofluorescence quantitative analysis.with 30 normal healthy persons as controls.Results As compared with the control group.plasma level of BNP increased significantly in patients with chronic cor pulmonale and hypertensive heart failure(P＜0.05),and that in those with hypertensive heart failure[(597±68)ng/L]Was significantly higher than that in those with cot pulmonale[(179±34)ng/L,P＜0.05]. Conclusion Plasma level of BNP can be used as an indicator to differentiate cor pulmonale from hypertensive heart failure both with dyspnea.