CAJ | 학술논문

目的探讨烧伤患者的焦虑抑郁症状与血浆皮质醇水平的关系.方法以烧伤患者33例为研究组,应用汉密顿抑郁量表(HAMD)和汉密顿焦虑量表(HAMA)为工具,于入院后0周、1周末和4周末分别评定烧伤患者的焦虑抑郁症状,并同步测定血浆皮质醇水平,分析焦虑抑郁症状量表分与血浆皮质醇水平的关系,并与本院30例体检者作对照.结果研究组的HAMD、HAMA总分在烧伤急性期(0周和1周末)均显著升高(P＜0.01),好转后恢复至正常水平.与对照组比较,研究组的血浆皮质醇水平在急性期显著升高(P＜0.01),随着烧伤的改善而恢复正常.研究组急性期(0周与1周末之间)血浆皮质醇水平的变化与HAMD、HAMA总分的变化呈正相关.结论烧伤患者在急性期存在不同程度的焦虑抑郁情绪,伴血浆皮质醇水平升高,此期需给予相应的药物治疗和心理干预.
목적 탐토소상환자적초필억욱증상여혈장피질순수평적관계.방법 이소상환자33례위연구조,응용한밀돈억욱량표(HAMD)화한밀돈초필량표(HAMA)위공구,우입원후0주、1주말화4주말분별평정소상환자적초필억욱증상,병동보측정혈장피질순수평,분석초필억욱증상량표분여혈장피질순수평적관계,병여본원30례체검자작대조.결과 연구조적HAMD、HAMA총분재소상급성기(0주화1주말)균현저승고(P＜0.01),호전후회복지정상수평.여대조조비교,연구조적혈장피질순수평재급성기현저승고(P＜0.01),수착소상적개선이회복정상.연구조급성기(0주여1주말지간)혈장피질순수평적변화여HAMD、HAMA총분적변화정정상관.결론 소상환자재급성기존재불동정도적초필억욱정서,반혈장피질순수평승고,차기수급여상응적약물치료화심리간예.
Objective To explore the the relationship between the anxiety-depression symptoms and the level of serium cortisone in patients with burn.Methods Totally 33 patients with burn (the study group) were evaluated with Hamilton depression scale(HAMD),Hamilton anxiety scale(HAMA) before treatment,after 1 week and after 4 weeks of treatment,at the same time,tested the level of serium cortisone,with 30 normal controls.Results During acute period,patients with bum had higher scores of HAMD and HAMA (P＜0.01) and decreased to normal level after recovery.Compared with the control group,the serium cortisone of bum patients significantly increased during acute period (P＜0.01) and recovered with bum improvement.There showed significant positive correlatin between the changes of serium cortisone and the changes of the total scores of HAMD and HAMA in the study group during acute period.Condusions During acute period,burn patients have some extent anxiety-depression symptoms with higher level of serium cortisone.This need drug-treatment and psychological interventions respectively.