现代口腔医学杂志
現代口腔醫學雜誌
현대구강의학잡지
JOURNAL OF MODERN STOMATOLOGY
2009年
6期
627-630
,共4页
曲勃颖%黄洋%赵晶%姜力铭%李海鹰%艾永华%姜秋
麯勃穎%黃洋%趙晶%薑力銘%李海鷹%艾永華%薑鞦
곡발영%황양%조정%강력명%리해응%애영화%강추
乳恒牙替换%破骨细胞%活化T细胞核因子
乳恆牙替換%破骨細胞%活化T細胞覈因子
유항아체환%파골세포%활화T세포핵인자
Replacement of primary and permanent teeth%Osteoclasts%Nuclear Factor of Active T cells
目的 通过观察犬乳恒牙替换过程中活化T细胞核因子(nuclear factor of active T cells,NFAT)NFATc1的表达探讨其在此过程中的作用及意义.方法 制备犬乳恒牙替换各阶段乳牙根、牙槽骨、恒牙胚的组织标本切片,用免疫组织化学方法检测NFATc1在犬乳恒牙替换期间的表达.结果 NFATc1在破骨细胞、恒牙胚成釉细胞、成牙本质细胞层中表达阳性.结论 NFATc1可能参与了犬乳恒牙替换生理过程中乳牙根、牙槽骨的吸收和恒牙胚的发育.
目的 通過觀察犬乳恆牙替換過程中活化T細胞覈因子(nuclear factor of active T cells,NFAT)NFATc1的錶達探討其在此過程中的作用及意義.方法 製備犬乳恆牙替換各階段乳牙根、牙槽骨、恆牙胚的組織標本切片,用免疫組織化學方法檢測NFATc1在犬乳恆牙替換期間的錶達.結果 NFATc1在破骨細胞、恆牙胚成釉細胞、成牙本質細胞層中錶達暘性.結論 NFATc1可能參與瞭犬乳恆牙替換生理過程中乳牙根、牙槽骨的吸收和恆牙胚的髮育.
목적 통과관찰견유항아체환과정중활화T세포핵인자(nuclear factor of active T cells,NFAT)NFATc1적표체탐토기재차과정중적작용급의의.방법 제비견유항아체환각계단유아근、아조골、항아배적조직표본절편,용면역조직화학방법검측NFATc1재견유항아체환기간적표체.결과 NFATc1재파골세포、항아배성유세포、성아본질세포층중표체양성.결론 NFATc1가능삼여료견유항아체환생리과정중유아근、아조골적흡수화항아배적발육.
Objective To study the expression of nuclear factor of active T cells NFATc1 during the replacement of primary and permanent teeth in dog.Methods The expression of NFATc1 was examined in the sections of the deciduous teeth roots, the alveolar bone and the permanent teeth germs by immunohistochemistry.Results NFATc1 positive cells were observed in the osteoclasts, ameloblasts and odontoblasts of the permanent teeth germs.Conclusion NFATc1 is involved in the resorption of deciduous teeth roots, alveolar bone, and the development of permanent teeth germs during the stages of the replacement of primary and permanent teeth.
