CAJ | 학술논문

血吸虫和血吸虫病的研究在2007年成果丰硕,通过PubMed以schistosome.schistosomiasis,Schistosoma为检索词共检索到2007年相关文献518篇,其中综述49篇.寻求敏感性好、特异性高的诊断方法仍是研究的热点,血吸虫病的治疗在寻求新靶标的同时需要重新思考策略和对象;血吸虫分子生物学的注意力从传统的基因研究转向了糖组学等后基因组领域;疫苗候选分子的研究则关注与代谢有关的分子,血吸虫病免疫机制的研究在动物及人群水平均有新的报道.此外,血吸虫病流行状况调查以及疾病负担评估显示,控制血吸虫病仍是各国在公共卫生方面不容忽视的课题.
혈흡충화혈흡충병적연구재2007년성과봉석,통과PubMed이schistosome.schistosomiasis,Schistosoma위검색사공검색도2007년상관문헌518편,기중종술49편.심구민감성호、특이성고적진단방법잉시연구적열점,혈흡충병적치료재심구신파표적동시수요중신사고책략화대상;혈흡충분자생물학적주의력종전통적기인연구전향료당조학등후기인조영역;역묘후선분자적연구칙관주여대사유관적분자,혈흡충병면역궤제적연구재동물급인군수평균유신적보도.차외,혈흡충병류행상황조사이급질병부담평고현시,공제혈흡충병잉시각국재공공위생방면불용홀시적과제.
Much progress has been made in researches on schistosome and schistosomiasis in the year of 2007. Totally 518 papers including 49 reviews published in this year were retrieved from PubMed database under the search terms of schistosome, schistosomiasis and Schistosoma. Among those, many were dedicated to the development of new diagnosis method with high sensitivity and high specificity. Strategies need to be re-de-fined regarding subject selection and drug usage. Integrating transcriptome, proteome and glycome analyses into Schistosorna biology research has generated a comprehensive picture of Schistosoma transcriptional and genomic diversity. Continuous efforts have been made on defining metabolism related molecules as vaccine candidates as well as on studies of immune mechanisms at both animal and population levels. Surveys on epidemiology of schistosomiasis and re-estimation of the global burden of schistosomiasis have led more concern to this infectious disease.