CAJ | 학술논문

目的探讨CT引导下放射性123I粒子植入治疗老年人晚期恶性肿瘤患者的疗效.方法收集同期78例老年晚期恶性肿瘤患者,采取自愿接受治疗原则将其分为两组.治疗组41例采用CT引导下放射性125I粒子植入治疗,粒子活度为29.6 MBq,处方剂量90～110Gy；对照组37例采用最佳支持治疗；所有患者均复查并随访,观察其近期疗效、生存质量及不良反应等情况.结果治疗组有效率为92.7％(38/41),疾病控制率97.6％(40/41),对照组有效率0,疾病控制率16.2％(6/37).治疗组生存质量高于对照组(P＜0.05),未见严重不良反应.结论放射性125I粒子植入治疗老年人晚期恶性肿瘤是一种安全而有效的方法,能提高患者生存质量.
목적 탐토CT인도하방사성123I입자식입치료노년인만기악성종류환자적료효.방법 수집동기78례노년만기악성종류환자,채취자원접수치료원칙장기분위량조.치료조41례채용CT인도하방사성125I입자식입치료,입자활도위29.6 MBq,처방제량90～110Gy；대조조37례채용최가지지치료；소유환자균복사병수방,관찰기근기료효、생존질량급불량반응등정황.결과 치료조유효솔위92.7％(38/41),질병공제솔97.6％(40/41),대조조유효솔0,질병공제솔16.2％(6/37).치료조생존질량고우대조조(P＜0.05),미견엄중불량반응.결론 방사성125I입자식입치료노년인만기악성종류시일충안전이유효적방법,능제고환자생존질량.
Objective To investigate the efficacy of CT guided radioactive 125I seed implantation on elderly patients with advanced malignancies.Methods 78 cases of elderly patients with malignant were collected and divided into two groups.41 cases of the treatment group were treated with CT guided radioactive 125I seed implantation.Particle activity was 29.6 MBq.The prescription dose was 90-110 Gy.37 cases of the control group were treated with optimized supportive care.Data from all of patients were to review and followup observation in short term efficacy,quality of life and side efforts.Results The total effective rate was 92.7 ％(38/41)and the disease control rate was 97.6 ％(40/41)in the treatment group.The control group was in the effective rate and 16.2 ％(16/37)in the disease control rate.The quality of life of the treatment group was higher than those in the control group(P＜0.05).And there is no obviously side efforts.Conclusion The treatment of elderly patients with advanced malignant tumors by 125I seed implantation was a safe and effective method.It can improve the quality of patients' life.