国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2008年
8期
693-694
,共2页
子痈%抑素类%胞间信号肽类和蛋白质类
子癰%抑素類%胞間信號肽類和蛋白質類
자옹%억소류%포간신호태류화단백질류
Eclampsia%Chalones%Intercellular Signaling Peptides and Proteins
目的 探讨重度子痫前期患者血胱抑素C(Cys C)及尿转化生长因子β1(TGF-β1)的临床意义.方法 选择重度子痫前期患者35例为实验组,正常晚孕妇女35例为对照组,测定两组血清中的Cys C与尿液中的TGF-β1水平.结果 重度子病前期患者血清Cys C与尿TGF-β1较对照组均明显增高(均P<0.01);重度子痫前期患者组中,血清Cys C水平与尿TGF-β1呈正相关(r=0.581,P<0.05).结论 在重度子痫前期中检测血清Cys C与尿TGF-β1水平,有助于评价肾功能损害程度,对重度子痫前期的诊断和治疗具有一定的指导意义.
目的 探討重度子癇前期患者血胱抑素C(Cys C)及尿轉化生長因子β1(TGF-β1)的臨床意義.方法 選擇重度子癇前期患者35例為實驗組,正常晚孕婦女35例為對照組,測定兩組血清中的Cys C與尿液中的TGF-β1水平.結果 重度子病前期患者血清Cys C與尿TGF-β1較對照組均明顯增高(均P<0.01);重度子癇前期患者組中,血清Cys C水平與尿TGF-β1呈正相關(r=0.581,P<0.05).結論 在重度子癇前期中檢測血清Cys C與尿TGF-β1水平,有助于評價腎功能損害程度,對重度子癇前期的診斷和治療具有一定的指導意義.
목적 탐토중도자간전기환자혈광억소C(Cys C)급뇨전화생장인자β1(TGF-β1)적림상의의.방법 선택중도자간전기환자35례위실험조,정상만잉부녀35례위대조조,측정량조혈청중적Cys C여뇨액중적TGF-β1수평.결과 중도자병전기환자혈청Cys C여뇨TGF-β1교대조조균명현증고(균P<0.01);중도자간전기환자조중,혈청Cys C수평여뇨TGF-β1정정상관(r=0.581,P<0.05).결론 재중도자간전기중검측혈청Cys C여뇨TGF-β1수평,유조우평개신공능손해정도,대중도자간전기적진단화치료구유일정적지도의의.
Objective To investigate the clinical value of surem eystatin C and urinary transforming growth factorβ1(TGF-β1)in patients with severe eclampsism.Methods Serum cystatin C and urinary transforming growth factorβ1 were examined in 35 severe eclampsism women(experiment group,n=35)and normal late pregnant women(control group,n=35).Results The levels of serum cystatin C and urinary transforming growth factorβ1 were both significantly increased in experiment group than those in control group(both P<0.01).The serum level of cystatin C was positively correlative with urinary TGF-β1 level in experiment group(r=0.581,P<0.05).Conclusion The detection of serum cystatin C and urinary transforming growth factorβ1 is useful to assess renal function lesion in patients with severe eclampsism,which contributes to the diagnosis and treatment of severe eclampsism.
