国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2010年
21期
1309-1312
,共4页
茶碱%慢性阻塞性肺疾病
茶堿%慢性阻塞性肺疾病
다감%만성조새성폐질병
Theophylline%Chronic obstructive pulmonary disease
茶碱类支气管舒张药价格便宜、使用方便,但治疗剂量与中毒剂量接近限制了其临床应用,近年研究表明小剂量茶碱除具有支气管舒张作用外,还具有抗炎和免疫调节作用,为茶碱在慢性阻塞性肺疾病的治疗提供了新的理论依据.
茶堿類支氣管舒張藥價格便宜、使用方便,但治療劑量與中毒劑量接近限製瞭其臨床應用,近年研究錶明小劑量茶堿除具有支氣管舒張作用外,還具有抗炎和免疫調節作用,為茶堿在慢性阻塞性肺疾病的治療提供瞭新的理論依據.
다감류지기관서장약개격편의、사용방편,단치료제량여중독제량접근한제료기림상응용,근년연구표명소제량다감제구유지기관서장작용외,환구유항염화면역조절작용,위다감재만성조새성폐질병적치료제공료신적이론의거.
Theophylline, as a bronchodilator medication, is cheap and convenient. But its clinical application is limited,because that its therapeutic ratio is small and most of the benefit occurs only when near-toxic doses are given. Recent years, research have shown that low-dose theophylline also has antiinflammatory and immune regulatory role, which provided a new theoretical evidence for theophylline in the treatment of chronic obstructive pulmonary disease.