CAJ | 학술논문

目的了解广州市海珠区围产儿死亡病例中发生出生缺陷的种类及分布情况,探讨出生缺陷对围产儿死亡的影响.方法数据来源于广州市各医院逐季上报的<围产儿数季报表>及汇总至省妇幼保健院的<出生缺陷登记卡>,本研究监测了2004年第四季度-2008年第三季度海珠区各所医院住院分娩孕28-w产后7d的围产儿死亡率和死亡围产儿中出生缺陷发生率.结果监测广州市海珠区5年中围产儿48268例,围产儿死亡病例555例,围产儿死亡率为11.5‰,围产儿死亡中发生出生缺陷的220例,出生缺陷发生率为36.64%,其中胎儿水肿综合征、唇腭裂、脑积水、先天性心脏病和四肢畸形排在死亡围产儿出生缺陷发生的前5位.结论出生缺陷是导致围产儿死亡的重要原因之一,应加强婚前生殖健康教育和医学检查,做好婚前保健,优生及孕产期保健,尽可能减少出生缺陷的发生.
목적 료해엄주시해주구위산인사망병례중발생출생결함적충류급분포정황,탐토출생결함대위산인사망적영향.방법 수거래원우엄주시각의원축계상보적<위산인수계보표>급회총지성부유보건원적<출생결함등기잡>,본연구감측료2004년제사계도-2008년제삼계도해주구각소의원주원분면잉28-w산후7d적위산인사망솔화사망위산인중출생결함발생솔.결과 감측엄주시해주구5년중위산인48268례,위산인사망병례555례,위산인사망솔위11.5‰,위산인사망중발생출생결함적220례,출생결함발생솔위36.64%,기중태인수종종합정、진악렬、뇌적수、선천성심장병화사지기형배재사망위산인출생결함발생적전5위.결론 출생결함시도치위산인사망적중요원인지일,응가강혼전생식건강교육화의학검사,주호혼전보건,우생급잉산기보건,진가능감소출생결함적발생.
Objective To investigate the types and distribution of perinatal death defects in Haizhu District of Guangzhou and look for of related factors birth defects.Methods The cases of perinatal were studied from the third quarter of 2004 to the third quarter of 2008 in most of hospitals in Haizhu District.The datas were from birth defects registration cards of Maternal and Child Health Hospital of Guangdong Province,which included the perinatal birth informations of every quarters from all hospitals.Results 48248 cases of perinatal of Haizhu District were monitored in this study.There are 555 cases of perinatal death and the perinatal mortality rate was 11.5‰.There were222 cases of perinatal birth defects of all perinatal deaths and the birth defect rate of perinatal death was 36.64%.Hydrops fetalis syndrome,cleft lip and palate,hydrocephalus,congenital heart disease and limb deformities are the top five defects in a variety of cases.Conclusion Birth defects is one of the major causes of perinatal death.It is important for us to promote reproduetive health education and pre-malital medical examination,enhance environmental awareness in pre-marital health,eugenic,and maternal health,which should minimize the occurrence of birth defects.