CAJ | 학술논문

目的探讨Graves病(GD)患者甲状腺组织剪切波速度的变化及其与促甲状腺激素(TSH)的相关性.方法应用声辐射力脉冲成像技术(ARFI)中声触诊组织量化技术(VTQ),对40例Graves患者及30例正常对照者的甲状腺组织进行超声弹性量化检测,分析GD患者甲状腺组织剪切波速度的变化及其与TSH的相关性.结果 GD患者甲状腺组织不同部位剪切波速度均低于正常对照组相应部位,差异有统计学意义(P ＜0.05).GD患者甲状腺组织剪切波速度在不同部位间差异无统计学意义,两两间比较差异均无统计学意义(P＞0.05),GD患者甲状腺组织平均剪切波速度与TSH呈中度正相关(r=0.707).结论甲状腺组织剪切波速度可作为GD诊断的一项辅助指标,可间接反映TSH的水平,为GD的治疗提供一定的参考.
목적 탐토Graves병(GD)환자갑상선조직전절파속도적변화급기여촉갑상선격소(TSH)적상관성.방법 응용성복사력맥충성상기술(ARFI)중성촉진조직양화기술(VTQ),대40례Graves환자급30례정상대조자적갑상선조직진행초성탄성양화검측,분석GD환자갑상선조직전절파속도적변화급기여TSH적상관성.결과 GD환자갑상선조직불동부위전절파속도균저우정상대조조상응부위,차이유통계학의의(P ＜0.05).GD환자갑상선조직전절파속도재불동부위간차이무통계학의의,량량간비교차이균무통계학의의(P＞0.05),GD환자갑상선조직평균전절파속도여TSH정중도정상관(r=0.707).결론 갑상선조직전절파속도가작위GD진단적일항보조지표,가간접반영TSH적수평,위GD적치료제공일정적삼고.
Objective To investigate the changes of the shear wave velocities on thyroid tissues in patients with Graves disease(GD) and its correlation with thyrotropin (TSH).Methods Forty GD patients and 30 health adults who underwent an ultrasound-based acoustic radiation force impulse (ARFI) technique,the shear wave velocity of thyroid tissues was obtained using virtual touch tissue quantification (VTQ) of ARFI technique,and the changes of the shear wave velocities on thyroid tissues with GD patients and its correlation with the serum TSH level were analyzed.Results The shear wave velocities of thyroid tissues in patients with GD was lower than that of normal,thas were significant difference( P ＜0.05),but there were no significant differences among different locations in GD patients( P ＞0.05).The shear wave velocities of thyroid tissues were correlated with the serum TSH level in patients with GD,the correlation coefficient was 0.707.Conclusions The shear wave velocity may be considered as a helpful index in diagnosing GD and indirectly reflect the serum TSH level,provide some reference for therapy of the GD.