国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
7期
557-560
,共4页
维生素D%哮喘%慢性阻塞性肺疾病%肺结核%呼吸道感染
維生素D%哮喘%慢性阻塞性肺疾病%肺結覈%呼吸道感染
유생소D%효천%만성조새성폐질병%폐결핵%호흡도감염
Vitamin D%Asthma%Chronic obstructive pulmonary disease%Pulmonary tuberculosis%Respiratory infectious diseases
除了维持钙盐代谢和骨骼的稳态以外,研究发现维生素D还可调控包括机体防御,炎症,免疫,损伤修复等在内的多种生理和病理生理过程.流行病学资料表明,血清低水平的维生素D与肺功能受损、炎症反应和感染性疾病相关.因此,支气管哮喘、慢性阻塞性肺疾病和肺部感染性疾病都可能与维生素D水平有关,但具体的机制尚不明确.因此,本文通过文献回顾,概述维生素D在肺部疾病,包括支气管哮喘、慢性阻塞件肺疾病、肺结核和呼吸道感染中的作用.
除瞭維持鈣鹽代謝和骨骼的穩態以外,研究髮現維生素D還可調控包括機體防禦,炎癥,免疫,損傷脩複等在內的多種生理和病理生理過程.流行病學資料錶明,血清低水平的維生素D與肺功能受損、炎癥反應和感染性疾病相關.因此,支氣管哮喘、慢性阻塞性肺疾病和肺部感染性疾病都可能與維生素D水平有關,但具體的機製尚不明確.因此,本文通過文獻迴顧,概述維生素D在肺部疾病,包括支氣管哮喘、慢性阻塞件肺疾病、肺結覈和呼吸道感染中的作用.
제료유지개염대사화골격적은태이외,연구발현유생소D환가조공포괄궤체방어,염증,면역,손상수복등재내적다충생리화병리생리과정.류행병학자료표명,혈청저수평적유생소D여폐공능수손、염증반응화감염성질병상관.인차,지기관효천、만성조새성폐질병화폐부감염성질병도가능여유생소D수평유관,단구체적궤제상불명학.인차,본문통과문헌회고,개술유생소D재폐부질병,포괄지기관효천、만성조새건폐질병、폐결핵화호흡도감염중적작용.
In addition to the role of vitamin D (VitD) in calcium and bone homeostasis.VitD modulates a variety of processes and regulatory systems including host defense,inflammation,immunity,and repair. Epidemiological data indicate that low levels of serum VitD is associated with impaired pulmonary function,increased incidence of inflammatory infectious or neoplastic diseases.Several lung diseases,all inflammatory in nature,may be related to activities of VitD including asthma,chronic obstructive pulmonary disease (COPD) and pulmonary infectious diseases.The exact mechanisms remain to been clarified.This review summarizes the role of VitD in pulmonary diseases,such as brochial asthma,COPD,tuberculosis and respiratory infections.
