CAJ | 학술논문

目的:研究三个时期糖尿病视网膜病变的多焦视网膜电图特征及其临床意义。方法:采用VERISⅣ视觉诱发反应图像系统测量和分析了34例非增殖期、15例增殖前期和15例增殖期糖尿病视网膜病变的多焦视网膜电图的差异。结果:与正常对照眼比较，增殖期糖尿病视网膜病变，多焦视网膜电图的N1、P1和N2潜伏期在整个直径约45°的测试野中均延长。在增殖前期，P1和N2潜伏期在测试野中半径10.5°到22.5°的范围内均延长。在非增殖期、增殖前期和增殖期，N1-P1和P1-N2反应密度（幅度/面积）在整个直径约45°的测试野中均下降。结论：在糖尿病视网膜病变早期诊断中，多焦视网膜电图的反应密度较潜伏期敏感，多焦视网膜电图对各期糖尿病视网膜病变均具有诊断价值。
목적:연구삼개시기당뇨병시망막병변적다초시망막전도특정급기림상의의。방법:채용VERISⅣ시각유발반응도상계통측량화분석료34례비증식기、15례증식전기화15례증식기당뇨병시망막병변적다초시망막전도적차이。결과:여정상대조안비교，증식기당뇨병시망막병변，다초시망막전도적N1、P1화N2잠복기재정개직경약45°적측시야중균연장。재증식전기，P1화N2잠복기재측시야중반경10.5°도22.5°적범위내균연장。재비증식기、증식전기화증식기，N1-P1화P1-N2반응밀도（폭도/면적）재정개직경약45°적측시야중균하강。결론：재당뇨병시망막병변조기진단중，다초시망막전도적반응밀도교잠복기민감，다초시망막전도대각기당뇨병시망막병변균구유진단개치。
To investigate the characteristics of the multifocal electroretinograms in non-proliferative, severe nonproliferative and proliferative stages of diabetic retinopathy (DR), sixty-four patients with DR were studied, of which 34 were in non-proliferative stage, 15 were in severe nonproliferative stage and 15 were in proliferative stage. The multifocal electroretinograms of the eyes with DR in the three stages were tested with VERIS IV system. In proliferative stages of DR, the latencies of N1, P1 and N2 components were prolonged in the field of 45 degrees in diameter; in severe nonproliferative stages of DR, the latencies of P1 and N2 components were prolonged in the ring band from 10.5° to 22.5° eccentricity; and in non-proliferative, severe nonproliferative and proliferative stages, the N1-P1 and P1-N2 response densities (amplitude/area) were attenuated in the field of 45 degrees in diameter. In conclusions, the latency and the response density of multifocal electroretinograms have different sensitivity in detecting the dysfunction of retina in different stages of DR；the response density is more sensitive than the latency in detection of early DR.